Pain injections for hip arthroscopy patients may not predict surgical outcomes

How best to treat and recover from complicated hip injuries is a growing field in orthopaedic medicine. While diagnostic hip injections are commonly performed for patients with labral tear to confirm the pain etiology, new research suggests that pain relief from this diagnostic injection may not predict better outcomes following arthroscopic hip surgery.



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No need to delay rotator cuff surgery, study shows

Delaying rotator cuff surgery on patients with shoulder stiffness may not be necessary, according to new research.



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For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach

Early surgery may not be the best treatment option for patients with Type V AC joint injuries, according to new research. Medical researchers showed military personnel returned to duty faster when surgery was not performed.



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Immunotherapy delays recurrence for stage III and IV ovarian cancers

Personalized medicine is getting closer to reality for women with late-stage ovarian cancer. An experimental immunotherapy is in the works that can target an individual woman’s tumor and extend the time period between initial treatment and the cancer’s return.



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Global health experts outline lessons to be learned from Ebola epidemic

While the international response to the Ebola epidemic included unprecedented measures that appeared to be gaining control of the outbreak by the end of 2014, the past year has also revealed critical weaknesses in the global public health system. Global health experts make specific recommendations to improve future responses.



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Key mechanism of chronic inflammatory pain discovered that could reduce drug doses

A new mechanism to treat chronic inflammatory pain has been discovered that could help reduce the drug doses necessary for treatments. The project concluded that the small potassium channel plays a fundamental role in regulating the neuronal excitability of the spinal cord.



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How X-Rays Play Their Role in Imaging?

Imaging using X-rays involve an X-ray tube that penetrates the body to produce a beam of x-rays. When the tube passes through the body, some parts of the X-ray beam energy get absorbed by the body, which is dubbed X-ray beam attenuation.



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C. difficile doubles hospital readmission rates, lengths of stay

Patients with Clostridium difficile infection (CDI) are twice as likely to be readmitted to the hospital as patients without the deadly diarrheal infection, according to a new study.



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Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

RESEARCH-active members of the public are to showcase how their vital work helps shape clinical research projects and improves care for patients at a free drop-in event in Sheffield City Centre on Wednesday 22 April.



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Bundled payments: Study finds causes of hospital readmissions following joint replacements

A new study identifies common causes of hospital readmissions following total hip and knee arthoplasty procedures among patients involved in a Bundled Payment Care Initiative. By finding these common causes, researchers believe quality can be increased and hospital costs decreased.



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Fracture liaison services prevent fractures and save lives

Using a simulation model, researchers have shown that the implementation of Fracture Liaison Services could considerably reduce the human and healthcare costs associated with osteoporotic fractures.



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Bio-marker set forms the basis for new blood test to detect colorectal cancer

Colorectal cancer is the third most common form of cancer globally and the second most common cause of cancer deaths. The chance of a cure is high if the cancer is detected early enough, but early detection is not a given. Researchers have identified bio-markers that can be incorporated in a new diagnostic test. This should make it possible to detect colorectal cancer in an early stage using a simple blood test, they say.



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Weight-loss surgery before joint replacement can improve outcomes in severely overweight patients

Bariatric surgery prior to joint replacement is a cost-effective option to improve outcomes in severely overweight patients, research demonstrates. It is well-known that obesity takes a toll on one's health. Bariatric surgery and subsequent weight loss reduces the risk of heart disease, diabetes and even some forms of cancer. But before now, the effect of bariatric surgery on joint replacement outcomes was not known.



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Sir Andrew Cash named second most exceptional NHS chief executive by Health Service Journal

SIR Andrew Cash, chief executive of Sheffield Teaching Hospitals NHS Foundation Trust, has been named the second most exceptional NHS chief executive in the country by a leading health journal.



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Research on medical abortion, miscarriage may change international routines

Two scientific studies are expected to form the basis of new international recommendations for the treatment of medical abortions and miscarriages. One of the studies shows that it is possible to replace the clinical follow-up examinations recommended today with medical abortions that include a home pregnancy test. The other study shows that midwives can safely and effectively treat failed abortions and miscarriages in rural districts of Uganda.



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Promising clinical trial results for ebola vaccines

Interim findings from a clinical trial (PREVAIL) in which two experimental Ebola vaccines were given to more than 600 people in Liberia indicate that the vaccines are safe for use in humans. Based on these positive results, the vaccines may continue into the next stage of clinical evaluation; a phase 3 trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.



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Stopping cellular quality-control mechanism can make chemotherapy more effective

A University of Rochester team found a way to make chemotherapy more effective, by stopping a cellular quality-control mechanism, according to a study published today in Nature Communications.



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Women with IBD may be at increased risk for developing cervical cancer

Women with inflammatory bowel disease (IBD) may be at increased risk of cervical dysplasia and cancer, according to a new study1 published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.



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Why Positive Thinking Doesn't (Always) Work



The year is 2011. I’m living out of a duffel bag, sleeping on my friends’ couch at night, dishwashing part-time at a pizza parlor because it’s the only work I can find in northern Maine at the end of the summer, and holding in my hands a huge medical bill that I am unable to pay. Oh yeah, and I have pneumonia. I call my friend, and within two minutes I’m crying. She tells me, “Look on the bright side.” I want to punch her in the face. Don’t get me wrong. I love my friend, a lot (and I would never actually want to cause her any harm). But when I’m at my worst, I don’t want anybody telling me to act my best.


It turns out there’s some science behind my feelings: A look at the research reveals positive thinking isn’t always all it’s cracked up to be. In fact, researchers are asking: What if embracing so-called “negative” states like failure, pessimism, insecurity, and uncertainty actually has a positive outcome 1 ?


It's Not All Rainbows and Unicorns


It's Not All Rainbows and Unicorns

It’s not until recently that people have started thinking of happiness as something everybody’s entitled to all of the time. And in the headlong pursuit of ever-present positivity, we might be shooting ourselves in the feet. Constant positive thinking, some researchers say, means a person can never relax — because that’s the moment a “negative” thought might squirm its way to the surface. And insisting that “everything works out” offers positive thinkers no back-up plan for when things don’t.


These criticisms are backed by a lot of research. One study found that when people think others expect them not to feel negative emotions, they end up feeling more negative emotions more frequently 2 . Another study found that people with low self-esteem who repeated a positive self-statement (“I’m a lovable person”) ended up feeling worse than people who didn’t repeat the phrase 3 . Some researchers have linked the pressure to “think positive” to personal self-blame (“If I can’t be happy, it must be my fault for not being positive enough”). Denial’s another potential side effect of positive thinking, and some experts even blame the current economic crisis partly on people’s refusal to consider potential negative outcomes.


In fact, too much positive thinking can actually be a sign of a mood disorder, says Mark Banschick, M.D., a psychiatrist and Greatist expert. People with bipolar disorder (or its variations, bipolar II and cyclothymia) experience states of excessive positive thinking called “mania” that can interfere with their experience of reality and cause them to engage in potentially self-destructive behavior (driving at 120 mph, doing lots of drugs, stealing — because “everything’s great and nothing can hurt me”).


Though a typical person doesn’t experience positivity at such a manic level, it is possible for the average Jane or Joe to get swept up by positive feelings, lose their judgment, and do something they wouldn’t normally do. Positive thinking can also become a way of avoiding necessary action, an issue Banschick sees in many male clients in their early 20s. People might say “everything’s fine” even when it’s not — it’s a way of convincing ourselves we’re doing something about a given situation (a crappy job, a looming deadline, an issue with a partner) without actually doing anything.


“People who use positive thinking as a defense are trying not to feel anxious when they should,” Banschick says. Some amount of anxiety is often necessary for motivating us to act in certain situations. Covering up this anxiety with a cheery face can actually make our situation worse because we’re less likely to address the underlying issue. But the sooner we take action, the less likely anxiety is to interfere with whatever it is we’re trying to do, says Julie Norem, professor of psychology and author of The Positive Power of Negative Thinking .


The Benefits of Being a Pessimist


The Benefits of Being a Pessimist

So some level of negativity might actually be good for us. One study found that people in negative moods can produce better-quality and more persuasive arguments than people in a positive mood. Negative moods can also improve memory and mental accuracy, and other research suggests that negative thinking might prompt us to think more carefully. In light of these findings, many researchers are criticizing what they see as exaggerated claims from the pro-positivity camp, and standing behind the benefits of negative thinking 4 .


Of particular interest is defensive pessimism, a strategy for managing anxiety, says Norem. It involves setting low expectations and being pessimistic about what might happen in a given scenario. Studies find the strategy helps people manage anxiety by mentally planning for the worst (giving people a greater sense of control). It also allows them to perform their best, typically because they work extra hard to ensure that possible negative outcomes don’t come to pass 1 5 .


By preparing for the worst, there’s a chance we actually decrease our suffering down the road 6 . In contrast, trying to “correct” negative thoughts can actually intensify them. Of course there’s a cultural component to positive thinking, and the relative benefits of negativity versus positivity vary depending on societal attitudes toward happiness in a given region. (For example, European Americans often find positive feelings to be more relevant to life satisfaction, while Asian Americans generally find negative feelings to be most relevant to assessments of overall happiness.) 7 8 .


The effectiveness of positive thinking is also highly dependent on individual factors like anxiety, coping mechanisms, and belief systems, so each person has to find what works for her or him 9 . But regardless of a person’s disposition, researchers suggest it might be better to acknowledge negative emotions instead of denying them — and then let them pass. An emerging style of psychotherapy, called Acceptance and Commitment Therapy (ACT), suggests we should accept that negative thoughts are guaranteed to come up. Instead of devoting energy to suppressing negativity, we should concentrate on identifying and committing to our values even amidst a swarm of negative thoughts.


The Takeaway


We’re certainly not advocating that everyone become a sourpuss for life. Just like negative thinking, positive thinking has its proven benefits, both physically and psychologically 10 . The trick is finding the balance between being optimistic and being realistic, Banschick says. In other words: Stop and smell the roses, but first check for dog poop on the sidewalk beneath your feet.


Originally published October 2012. Updated March 2015.



Works Cited



  1. A two-factor model of defensive pessimism and its relations with achievement motives. Lim, L. Nanyang Technological University. Journal of Psychology, 2009 May;143(3):318-36

  2. Feeling bad about being sad: the role of social expectancies in amplifying negative mood. Bastian, B., Kuppens, P., Hornsey, MJ, et al. School of Psychology, University of Queensland, Australia. Emotion, 2012 Feb;12(1):69-80

  3. Positive self-statements: power for some, peril for others. Wood, JV, Perunovic, WQ, Lee, JW. Department of Psychology, University of Waterloo, Canada. Psychological Science, 2009 Jul;20(7):860-6

  4. Positive Psychology in Cancer Care: Bad Science, Exaggerated Claims, and Unproven Medicine. Coyne, J. and Tennen, H. Annals of Behavioral Medicine, 2010 February; 39(1): 16-26

  5. A motivational analysis of defensive pessimism and self-handicapping. Elliot, AJ, Church, MA. Department of Clinical and Social Sciences in Psychology, University of Rochester, New York. Journal of Personality, Jun;71(3):369-96

  6. The pain was greater if it will happen again: the effect of anticipated continuation on retrospective discomfort. Galak, J. and Meyvis, T. Tepper School of Business, Carnegie Mellon University. Journal of Experimental Psychology: General, 2011 Feb;140(1):63-75

  7. What constitutes a good life? Cultural differences in the role of positive and negative affect in subjective well-being. Wirtz, D., Chiu, CY, Diener, E., et al. Department of Psychology, East Carolina University. Journal of Personality, 2009 Aug;77(4):1167-96

  8. The dynamics of daily events and well-being across cultures: when less is more. Oishi, S., Diener, E., Choi, DW, et al. Department of Psychology, University of Virginia. Journal of Personal and Social Psychology, 2007 Oct;93(4):685-98

  9. Information seeking of high- and low-anxiety subjects after receiving positive and negative self-relevant feedback. Frey, D., Stahlberg, D., Fries, A. Journal of Personality, 1986 Dec;54(4):694-703

  10. Optimism and physical health: a meta-analytic review. Rasmussen, H.N., Scheier, M.F., Greenhouse, J.B. Institute for Educational Research and Public Service, University of Kansas, Lawrence, KS. Annals of Behavioral Medicine, 2009 Jun;37(3):239-56









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Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia.



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Roseroot extract may be beneficial for treating major depressive disorder

Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine led by Jun J. Mao, MD, MSCE, associate professor of Family Medicine, Community Health and Epidemiology and colleagues at the Perelman School of Medicine of University of Pennsylvania.



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Veterans with PTSD at higher risk of developing heart failure

In a study of more than 8,000 veterans living in Hawaii and the Pacific Islands, those with posttraumatic stress disorder had a nearly 50 percent greater risk of developing heart failure over about a seven-year follow-up period, compared with their non-PTSD peers.



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Doctors and Patients - 9 Important Things You Should Know For Your Health

To help you make some healthy choices, consider the following. Here are some common mistakes that doctors make, which could lead to death and suffering if not picked up on. To blatantly ignore any of these errors is the same as driving your car out of the garage and going on a long journey, knowing the breaks could fail anytime...



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Griffith research examines GPs’ confidence in providing nutritional advice to patients

The role of nutrition as part of a healthy lifestyle is well understood by the medical profession but whether this information is easily conveyed to patients is another matter. How much confidence GPs have in providing nutritional advice to their patients is now the subject of research by Griffith University’s Dr Lauren Ball.



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Experts unveil strategic roadmap to advance treatments for people with lymphoma

A committee of lymphoma experts today unveiled a strategic roadmap identifying key priority areas in both infrastructure and research that will be critical for advancing treatments for people with lymphoma.



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Moffitt study highlights that LGBTQI populations face health care disparities

The lesbian, gay, bisexual, transgender/transsexual, queer/questioning and intersex (LGBTQI) population has been largely understudied by the medical community. Researchers at Moffitt Cancer Center found that the LGBTQI community experience health disparities due to reduced access to health care and health insurance, coupled with being at an elevated risk for multiple types of cancer when compared to non-LGBTQI populations.



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German Neuroscience Society “FEI Technology Award” goes to Benjamin Judkewitz

FEI Munich, a subsidiary of FEI Company (NASDAQ: FEIC) is pleased to announce Benjamin Judkewitz as the 2015 recipient of the German Neuroscience Society “FEI Technology Award.”



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Anti-diabetic medication activates brain sensors, promotes weight gain

Medication used to treat patients with type II diabetes activates sensors on brain cells that increase hunger, causing people taking this drug to gain more body fat, according to researchers at Georgia State University, Oregon Health and Science University, Georgia Regents University and Charlie Norwood Veterans Administration Medical Center.



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New Ebola vaccine shows promise in first phase 1 clinical trial

Results from the first phase 1 trial of an Ebola vaccine based on the current (2014) strain of the virus are today published in The Lancet. Until now, all tested Ebola virus vaccines have been based on the virus strain from the Zaire outbreak in 1976. The results suggest that the new vaccine is safe, and provokes an immune response in recipients, although further long-term testing will be needed to establish whether it can protect against the Ebola virus.



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TNT announces opening of healthcare hub in Heerlen, the Netherlands

Today TNT will open an international transport hub in Heerlen, the Netherlands, dedicated to the shipping of medical devices to European hospitals and clinics.



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Griffith study explores how beer can be manipulated to improve its rehydration potential

It was only recently that Griffith University research showed that it’s possible to improve the hydrating effects of beer without killing off its taste.



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Study identifies common causes of hospital readmissions following joint replacements procedures

A new study from researchers at NYU Langone's Hospital for Joint Diseases identifies common causes of hospital readmissions following total hip and knee arthoplasty procedures.



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Guinean Government initiates first efficacy trial of Ebola vaccine in Basse-Guinée

The Guinean Government with the World Health Organization initiated the very first efficacy trial of an Ebola vaccine this week in an affected community of the Basse-Guinée, one of the areas where most Ebola cases are found in the country.



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Data demonstrates benefits associated with use of EXPAREL in hip, knee replacement patients

Pacira Pharmaceuticals, Inc. today announced data demonstrating the benefits associated with the use of EXPAREL (bupivacaine liposome injectable suspension) in a study of over 2,200 hip and knee replacement patients.



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New tool can measure cardiovascular risk in persons aged 40 or older

For the first time, scientists have developed a new risk score that can predict the 10-year risk of developing heart disease or having a stroke in persons aged 40 years or older in any world country.



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New report explores global issues affecting confidence, hesitation about polio vaccines

A decade on from the Northern Nigeria polio vaccination boycott and its global costs to the polio eradication initiative, a new report examines global issues affecting confidence and hesitation about vaccines since the new millennium.



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3D respiratory tissue model shown to be effective for measuring impact of chemicals

A 3-dimensional model of human respiratory tissue has been shown to be an effective platform for measuring the impact of chemicals, like those found in cigarette smoke, or other aerosols on the lung.



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Study sheds light on cataract development

The motion of coins in a "Penny Pusher" carnival game is similar to the movement of cells in the eye's lens, as described in a new study published in Investigative Ophthalmology & Visual Science (IOVS).



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Zyga reports commercial use of modernized SImmetry Sacroiliac Joint Fusion System for low back pain

Zyga Technology, Inc., a medical device company focused on the design, development and commercialization of minimally invasive devices to treat underserved conditions of the lumbar spine, today announced the launch and first commercial use of an updated SImmetry Sacroiliac Joint Fusion System. The surgery was performed by Dr. Brett Menmuir.



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Study: 70% of nurses in Scotland lack confidence in new delayed discharge target in hospitals

As the Scottish Government prepares to introduce a new two-week discharge target in hospitals from 1st April 2015, a new study has found 70 per cent of nurses in Scotland lack confidence in the policy and do not believe it will help reduce delays.



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Taconic, Cellaria partner to facilitate use of patient-derived xenografts for oncology research

Taconic Biosciences and Cellaria Biosciences today announced that the two companies have entered into a scientific collaboration designed to facilitate and improve the utility of patient-derived xenografts (PDXs) in animal models for oncology and immuno-oncology research. Cellaria’s novel methodologies for generating cells from patient tumors will complement Taconic’s industry-leading portfolio of tissue humanized mouse models, which are well-suited as hosts for PDXs.



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apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

apceth, a global leader in engineered cell therapies, today announced the successful completion of the Phase I and initiation of the Phase II part of its ongoing monocentric Phase I/II clinical trial TREAT-ME 1 with the engineered cell therapeutic product Agenmestencel-T, at the Klinikum Grosshadern in Munich.



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NHS England launches online directory to support people with mental health conditions

Yesterday, the new NHS Choices Mental Health Apps Library was launched to the public. Big White Wall was among the first five mental health services to be featured in this online directory.



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Research reveals why people with type 1 diabetes are unable to control blood glucose levels

TEACHING people with type 1 diabetes how to embed lifelong habits such as carbohydrate counting into everyday life rather than as part of week-long education programmes could significantly reduce their risk of complications from the disease, according to new research.



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DePuy Synthes inks sales agreement with Radlink to offer real-time image guidance with hip replacement systems

DePuy Synthes Companies has signed an exclusive worldwide sales agreement with Radlink, Inc., an emerging global leader in advanced medical imaging technology, to offer real-time image guidance with its hip replacement systems. The agreement further demonstrates DePuy Synthes Companies’ ongoing commitment to help improve patient outcomes, increase patient satisfaction and reduce costs.



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DePuy Synthes adds four new products to adult deformity portfolio

DePuy Synthes Companies announced the addition of four new products to its adult deformity portfolio as well as a new education offering, continuing its expansion of one of the broadest spine portfolios in the industry. The products were displayed by DePuy Synthes Spine at the 81st annual meeting of the American Academy of Orthopaedic Surgeons.



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Ebola more likely to be fatal for young children

Ebola progresses more quickly and is more likely to be fatal for children under five, according to new research. An international group of scientists led by Imperial College London and the World Health Organization analysed data on Ebola cases in children under 16 during the current outbreak in Guinea, Liberia and Sierra Leone, comparing them to cases in adults.



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Regeneron announces FDA approval of EYLEA (aflibercept) Injection for diabetic retinopathy

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has approved EYLEA (aflibercept) Injection for the treatment of diabetic retinopathy in patients with diabetic macular edema (DME). In 2014, the FDA granted EYLEA Breakthrough Therapy designation and Priority Review for the treatment of diabetic retinopathy in patients with DME.



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TeleHealth Services, Samsung complete new SmarTigr system to improve patient-provider communication

TeleHealth Services, the nation’s leading provider of hospital televisions and interactive patient engagement solutions, announced through their partnership with Samsung Electronics America, Inc., the completion of a new patient engagement solution called SmarTigr.



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GFT505 demonstrates dose-dependent efficacy on primary endpoint in phase 2 NASH trial

GENFIT, today announces topline results of the phase 2 GOLDEN-505 trial in NASH. Due to the unexpected rate of resolution of NASH in patients randomized to placebo who had early NASH (NAS of 3, placebo response rate>57%), along with the high number of sites for a limited sample size, the study as initially designed did not enable the trial to meet directly the primary endpoint.



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Minimally-invasive surgery offers long-term cost savings for healthcare system, less trauma for patients

Adding to the clinical benefits and improved patient outcomes associated with minimally-invasive surgery (MIS), Medtronic plc today highlighted new data demonstrating that patients who underwent minimally invasive colon resection procedures were able to leave the hospital faster, visit their doctors less for follow up care and take fewer medicines than those who underwent open surgery.



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LifeCodexx announces promising results from proof-of-principle study of qPCR-based NIPT assay

LifeCodexx AG today reports the successful outcome of a proof-of-principle of its novel assay for non-invasive prenatal testing (NIPT assay) based on quantitative real-time PCR (qPCR). This NIPT assay, designed to determine fetal aneuploidies from maternal blood, will offer significant advantages, such as enhanced test performance at affordable prices, over other prenatal examination methods.



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WHO report: Access to new medicines requires transparency, collaboration

As the number of new medicines introduced in Europe rises, governments are finding it increasingly difficult to afford them, according to a comprehensive study released today by the WHO Regional Office for Europe.



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Greatist Workout of the Day: Friday, March 27th



This series of GWODs was designed exclusively for Greatist by Bodeefit. For more information about the exercises in this workout, or to see video demos of each movement, follow the links below the graphic. Be sure to note the results of your workout so you can track your progress as you go.


Before you tackle this workout, try this quick and effective full-body warm-up. It's just five simple moves but hits every major muscle group and gets your heart pumping.


Greatist Workout of the Day: Finish Strong

Finish Strong


Complete as many rounds of the following as safely possible in 10 minutes.


3 Wall Walks

6 Tuck Jumps

9 V-Ups


Want to kick up the intensity? Speed it up. And don't forget to check back tomorrow for a totally new (but equally awesome) GWOD!








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New, streamlined solution for the E-health sector

Today, hospitals and clinics face a dilemma. On the one hand, they are under increasing efficiency pressure, while on the other hand, demands on patient comfort are on the rise.



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In debated surgical procedure, technique trumps technology

Modern technology for healing distal femur fractures is as safe and effective as its more established alternative, without a potential shortfall of the older approach, a team of orthopedic surgeons has found.



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Two new ways to identify joint replacement patients at risk for post-operative complications

Orthopedic surgeons have developed two new prediction tools aimed at identifying total hip and knee replacement patients who are at-risk of developing serious complications after surgery. "Improved anesthesia and rehabilitation techniques have made outpatient and overnight stay for total hip and total knee replacements more common than ever," said a study's lead investigator. "At the same time, pressures on hospitals to lower costs have led to an across-the-board emphasis on shortening or even eliminating in-hospital stays. While shorter stays are obviously a major overall benefit, we have to make sure that we identify patients who are at greater risk of complications and should thus not have their knee or hip replaced on an outpatient or overnight basis. Our tool provides this guidance."



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Cellworld 2015 conference to be held in Downtown San Francisco on Sept. 21-22, 2015

Finesse Solutions announced Cellworld 2015, a new event that is specifically designed for innovators, visionaries and senior executives in bio-processing.



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Nanolek, Green Cross sign strategic deal to commercialize biologics in the Russian market

Green Cross, a South Korean biopharmaceutical company, and Nanolek, a Russian pharmaceutical company, today announced that they have entered into a strategic partnership agreement for the commercialisation of Green Cross' biologics in the Russian market.



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Top scientists to attend 3rd annual Helmholtz-Nature Medicine Diabetes Conference

As a unique scientific panel it brings together top scientists as well as promising young researchers from different disciplines in a personal and selected ambience.



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Brainstorm Cell Therapeutics provides business update, announces financial results for 2014

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced financial results for the three months and year ended December 31, 2014.



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Iceland paint a genomic picture for an entire nation

Researchers in Iceland have published the largest ever studies of whole-genome data and effectively deduced the genetic code of “an entire nation.”



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Living Better While Living Longer

We are living longer today than ever. As life expectancies increase, so does the need for new tools to promote self-sufficiency and social contact.



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New Autism-Causing Genetic Variant Identified

Using a novel approach that homes in on rare families severely affected by autism, a Johns Hopkins-led team of researchers has identified a new genetic cause of the disease. The rare genetic variant offers important insights into the root causes of autism, the researchers say. And, they suggest, their unconventional method can be used to identify other genetic causes of autism and other complex genetic conditions.



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Metabolic imbalance can trigger respiratory diseases in early childhood

An imbalance in our metabolism can trigger inflammatory processes in the body and activate the immune system. In a recent study, published in the Journal of Allergy and Clinical Immunology, UFZ researchers have been able to show that this applies even to newborns and children under one year of age, and is correlated with the development of respiratory diseases in early childhood.



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Transition announces positive results from ELND005 AME and renal clearance studies

Transition Therapeutics Inc. today announced results from two phase 1 clinical studies of neuropsychiatric drug candidate ELND005. These studies, an absorption-metabolism-excretion ("AME") study and a renal clearance study, are specialized clinical pharmacology trials that are required by the United States Food and Drug Administration for the approval of most drugs in development.



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Successful Weight Loss Now, What Are You Up Against?

In order for you to lose weight successfully, you need to know just what you are up against. There are billions of dollars spent each year on marketing, each dollar targeting you. Designed to make you eat their food and drink their drinks. Many marketers use the field of neuro-marketing to design their campaigns. Testing eye tracking in advertisements, using functional MRI to discover exactly what makes us buy what we do. Using every aspect of persuasion to influence you to do what they want you to do.



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USF scientists identify potential compounds to improve cardiovascular system, small vessel disease

University of South Florida scientists have identified a group of compounds with the potential for beneficial effects on the cardiovascular system and small vessel disease while researching grape seed extracts discovered at USF.



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Study finds gaps in information-sharing strategies between hospitalists and PCPs

Coordinating patient care between hospital clinicians and primary-care physicians is a significant challenge due to poor communication and gaps in information-sharing strategies, according to a study led by physicians at the School of Medicine of the University of Colorado Anschutz Medical Campus.



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Rice University study reveals carbon nanotube fibers can provide two-way connection with neurons

Carbon nanotube fibers invented at Rice University may provide the best way to communicate directly with the brain.



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Keeping ahead of the curve - get the most out of challenging qPCR assays

Ideal for both experienced and novice qPCR users, the talk will cover the benefits and limitations of melt curve analysis and suggest troubleshooting techniques. Attendees will learn how to analyze melt curves to extract reliable data from challenging experiments.



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Position statement on promise, challenges of non-invasive prenatal testing

Two of the world's largest professional societies of human geneticists have issued a joint position statement on the promise and challenges of non-invasive prenatal testing (NIPT), a new procedure to test blood drawn from pregnant mothers for Down syndrome and other chromosomal disorders in the fetus.



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National Center for Medical-Legal Partnership to host conference to discuss on health, legal problems

The National Center for Medical-Legal Partnership, part of Milken Institute School of Public Health at the George Washington University, will host its tenth annual conference on April 9-10, 2015, in McLean, Virginia to discuss how to better address the social and legal problems negatively impacting the health of 50 million low-income Americans.



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Patients with sickle cell disease have sleep disordered breathing problem

A new study in the Journal of Clinical Sleep Medicine revealed that 44 percent of adults with sickle cell disease who report trouble sleeping actually have a clinical diagnosis of sleep disordered breathing, including sleep apnea, which lowers their oxygen levels at night.



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Study: HBV exposure increases immune system maturation of infants

A Singapore led study has shown that Hepatitis B Virus Infection (HBV) exposure increases the immune system maturation of infants, which may give a better survival advantage to counteract bacterial infection during early life. These findings radically modify the way that HBV vertical infection of neonates (mother-to-child) is portrayed, and present a paradigm shift in the approach to treatment of patients with chronic hepatitis B.



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UVA researchers develop compound that could lead to improved leukemia treatments

Researchers at the University of Virginia School of Medicine have developed a compound that delays leukemia in mice and effectively kills leukemia cells in human tissue samples, raising hopes that the drug could lead to improved treatments in people. The researchers call it an exciting "new paradigm" for treating leukemia.



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We Found the Perfect Mattress (and Never Want to Get Out of Bed)



Stuff We Love: Casper Mattress


Casper Mattress


To say we’re obsessed with sleep is probably an understatement. We soak up all the sleep advice we come across, from the tricks to sleep absolutely anywhere to the foods we should eat and yoga moves we should do to fall asleep fast. But sometimes our sleep troubles can’t be solved with these quick hacks. We have to get back to basics—past the pillow and the 1000-thread-count sheets—to the mattress. And the one we can’t stop bragging about is the Casper mattress.


These foam mattresses are made in the good ol’ U.S.A. with a Goldilocks-style comfort—not too hard, not too soft, but just right. The first time we laid down on the Casper (right after taking it out of its jack-in-the-box packaging) we didn’t want to put any sheets on—it was comfy enough to simply snuggle on our new cloud (er, bed). The mattresses are made from memory foam that forms perfectly to every curve of your body and latex, which keeps you cool on even the warmest nights.


It’s super easy to get your very own Casper. The mattresses are only available online and they ship to you in five days or less (sometimes even by bicycle!). If you’re on the market for a new mattress, look no further than Casper—you won’t be disappointed.








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Immunotherapy reverses memory problems in animal model of Alzheimer's disease

A new study from the University of Texas Medical Branch at Galveston has revealed that a single dose of an immunotherapy reverses memory problems in an animal model of Alzheimer's disease. The article appears in the March 25 issue of the Journal of Neuroscience.



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UCLA-led team validates first standardized protocol for tracking early signs of Alzheimer's disease

After six years of painstaking research, a UCLA-led team has validated the first standardized protocol for measuring one of the earliest signs of Alzheimer's disease -- the atrophy of the part of the brain known as the hippocampus.



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Mount Sinai researchers reprogram blood cells into iPSCs to study genetic origins of MDS

Induced pluripotent stem cells (iPSCs) -- adult cells reprogrammed back to an embryonic stem cell-like state--may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.



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Researchers find strong association between lifestyles of indigenous communities and gut microbiome

An international team of researchers led by the University of Oklahoma has discovered a strong association between the lifestyles of indigenous communities and their gut microbial ecologies (gut microbiome), a study that may have implications for the health of all people.



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Researchers identify possible blood biomarkers for concussion

By looking at the molecular aftermath of concussion in an unusual way, a team of researchers at Brown University and the Lifespan health system has developed a candidate panel of blood biomarkers that can accurately signal mild traumatic brain injury within hours using standard, widely available lab arrays.



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Bioquell QUBE to be showcased at EAHP 2015

The latest generation isolator, the Bioquell QUBE, will be showcased on stand 117 at the European Association of Hospital Pharmacists 20th annual conference in Hamburg, 25th to 27th March 2015.



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Challenges facing scientific community in the 21st century

Embracing revolutionary new techniques and answering questions about research funding are just two of the challenges facing the scientific community in the 21st century.



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K2M announces enhanced complex spine portfolio with addition of its innovative NILE™ alternative fixation spinal system

NILE features low-profile, robust implants and intuitive and light ergonomic instruments, intended to provide stabilization between the spine and the rod, and to allow for reduction, translation, compression and distraction while sparing the anatomy...



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Research opens door to new prostate cancer treatment

Researchers from the Centenary Institute’s Origins of Cancer Program have discovered new links between nutrition and prostate cancer.



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ASH welcomes new anti-illicit tobacco strategy launched by Government

ASH welcomed the Government’s refreshed anti-illicit tobacco strategy launched today. The new strategy had been pre-announced in the Budget, which noted that it would not only protect public finances but also “help meet public health objectives by driving down smoking prevalence.”



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AdverseEvents launches RxCost to determine economic impact of prescribing particular drugs

AdverseEvents Inc., a leading healthcare informatics company, today launched RxCost, the first methodology to identify the total costs of adverse drug reactions (ADRs) associated with FDA-approved drugs.



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5 Facts That Make Weight Loss For Women Unique

When it comes to weight loss for women, it's important to remember that a woman's weight loss plan will not be the same as a man. Here are 5 bizarre truths about healthy weight loss for women.



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How To Get And Stay Motivated To Lose Weight

Motivation is one of the most important factors in determining how successful we are at achieving our goals. It is the driving force that keeps us on our path when we reach stumbling blocks and failures. And we will reach stumbling blocks and failures because they are a part of being human. No one person has ever become successful without first failing. The question isn't if you'll fail but what you'll do when you DO fail. The trick is to fail forward. In other words, when you fail get up and move forward. Motivation levels will also change each day depending upon how you feel or how you experience certain situations. Weight loss motivation can sometimes be particularly challenging because although you may understand that weight loss, to be permanent, is a slow process, in this fast paced world we all want the weight gone NOW.



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AstraZeneca, HSCI collaborate to find new treatments for diabetes

AstraZeneca today announced that it has entered into a five-year research collaboration with the Harvard Stem Cell Institute to adapt a technique that creates human beta cells from stem cells for use in screens of AstraZeneca’s compound library in the search for new treatments for diabetes.



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C3BS plans to open new U.S.-based facility to manufacture C-Cure for use in Phase III trial

Cardio3 BioSciences, a leader in the discovery and development of engineered cell therapies, today confirmed plans to open a new U.S.-based manufacturing facility in Rochester, Minnesota. The facility will support the Company’s current and anticipated manufacturing needs in the United States for both the Phase III clinical trial evaluating lead cardiovascular product candidate C-Cure (CHART-2), and its recently acquired CAR T-cell therapies’ portfolio.



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Eight students to continue medical education in St. Luke’s Graduate Medical Education programs

Friday, March 20 was the end of a long process for medical students, said Dr. Joel Rosenfeld, MD, M.Ed, FACS, Chief Academic Officer, St. Luke’s University Health Network. “National Match Day is truly a milestone for every medical student across the country. This is the day when medical residency programs match with their highest-ranked medical students, and medical students learn where they will continue their medical training as residents.”



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New Quest Diagnostics study analyses impact of ACA in promoting earlier diagnosis of diabetes

People in states that expanded Medicaid under the Affordable Care Act (ACA) are far more likely to be newly identified with diabetes than in states that elected not to expand the public health care program, finds a new study by researchers at Quest Diagnostics.



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BeyondSpring files two patent applications to expand therapeutic scope of Plinabulin

BeyondSpring Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on the development of innovative cancer therapies, today announced that it has filed two new method of treatment patent applications with the United States Patent and Trademark Office to cover methods of treating brain tumors as well as cancers expressing a mutant form of RAS protein through administration of the Company’s lead compound, Plinabulin.



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Novasep, Celladon sign agreement to develop and supply MYDICAR drug substance

Novasep, a leading supplier of services and technologies for the life sciences and chemical industries, and Celladon Corporation, a clinical-stage cardiovascular gene therapy company, today announce that they have signed a Development, Manufacturing and Supply Agreement pursuant to which, if supported by upcoming MYDICAR clinical data, Novasep would manufacture MYDICAR drug substance through 2018 with extension options through 2020.



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Arno Therapeutics' AR-42 with cisplatin demonstrates anti-tumor effect in bladder cancer models

Arno Therapeutics, Inc., a clinical stage biopharmaceutical company primarily focused on the development of oncology therapeutics, today announced that data from a preclinical study demonstrate its histone-deacetylase (HDAC) inhibitor AR-42 in combination with cisplatin has a synergistic anti-tumor effect in bladder cancer models.



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TB Alliance, U.S. Fund for UNICEF partner to bring new TB treatments for children

TB Alliance has announced a new partnership with the U.S. Fund for UNICEF that will dramatically increase the scope and impact of child and maternal health programs around the world to include the diagnosis and treatment of pediatric tuberculosis (TB), a significant cause of child mortality.



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Theravectys gets authorization to produce lentiviral vectors for clinical use and CAR-T cell-based immunotherapy

THERAVECTYS, a clinical development biotechnology company that focuses on the development of therapeutic vaccines and immunotherapies, proudly announces that its manufacturing plant has obtained the status of a pharmaceutical manufacturing establishment, granted by the French National Agency for Medicines and Health Products Safety.



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TSRI scientists identify enzyme that maintains healthy periods of inactivity in HSCs to prevent anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations. In the case of blood stem cells (also called hematopoietic stem cells or HSCs), this can lead to blood cancers, a loss of blood cells and an impaired ability to fight disease.



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Claritas to present data on Pediatric Neurological Exome Assay and new sequencing approach at ACMG 2015

Claritas Genomics will present data on the quality of parallel multi-technology sequencing, a comparison of the company’s phenotypically driven Pediatric Neurology Exome Assay to whole exome and panel-based approaches, three-part reports for rapid results reporting, and the clinical utility of the Neurology Exome’s tailored approach compared to other tests currently on the market.



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Denator partners with Maastricht University to develop sample stabilization approaches for clinical applications

Denator AB announced today that the company has entered into a 2-year collaboration with the Maastricht MultiModal Molecular Imaging Institute (M4I) of Maastricht University, the Netherlands. As part of the collaboration, Denator will work closely with the M4I Division of Imaging Mass Spectrometry, headed by university professor Ron Heeren, to jointly develop and evaluate innovative sample stabilization approaches for clinical applications.



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Are Cheat Days Actually Hurting Your Health?

Greatist Workout of the Day: Thursday, March 26th



This series of GWODs was designed exclusively for Greatist by Bodeefit. For more information about the exercises in this workout, or to see video demos of each movement, follow the links below the graphic. Be sure to note the results of your workout so you can track your progress as you go.


Before you tackle this workout, try this quick and effective full-body warm-up. It's just five simple moves but hits every major muscle group and gets your heart pumping.


Greatist Workout of the Day: The Griff

The Griff


Complete as many rounds of the following circuit as safely as possible in 20 minutes.


10 Dips

8 Box Jumps

6 Handstand Push-Ups


Want to kick up the intensity? Use a tall box on the box jumps. And don't forget to check back tomorrow for a totally new (but equally awesome) GWOD!








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Immunomagnetic assay with microfluidic technology can capture, manipulate circulating tumor cells

To quantify rare tumor markers that will allow oncologists to make prognoses and select therapies, John X.J. Zhang, PhD led a team of bioengineers from the Thayer School of Engineering at Dartmouth in demonstrating a novel system that couples nano-engineered particles and microfluidic chips for capturing and manipulating circulating tumor cells (CTCs).



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Having strong purpose in life may give you better brain health

Having a strong sense that your life has meaning and direction may make you less likely to develop areas of brain damage caused by blockages in blood flow as you age. This research is reported in the American Heart Association's journal Stroke.



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After decades of debate, there is no generally accepted definition for ‘natural’ food product

After decades of debate there remains no generally accepted definition of a "natural" food product. Regulatory agencies have refused to settle the issue but may be under new pressure from consumer lawsuits, according to a new study in the Journal of Public Policy & Marketing.



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Study explores outcomes of thyroid surgery in professional singers

A diagnosis of thyroid cancer can be devastating to professional singers, because surgical removal of the thyroid commonly causes voice changes. Massachusetts Eye and Ear surgeons developed a neural monitoring system to be used intraoperatively to improve outcomes.



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Study: Early improvements not sustained in patients treated with PRP injection for facet joint arthropathy

Early gains in pain relief, behavioral markers and function were not sustained in patients treated with platelet-rich plasma (PRP) injection for facet joint arthropathy, new research shows. Results were available at the 31st Annual Meeting of the American Academy of Pain Medicine.



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Soils play a major role in radiation control, shows research

Radiation suddenly contaminates the land your family has farmed and lived on for generations. Can soil play a role in protecting crops and human health?



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New approach to treating B-ALL tumour disease

B cell acute lymphoblastic leukaemia, or B-ALL, is the most common tumour disease in children and also occurs in adults. It develops when signalling pathways in immature B cells, or pre-B cells, are dysregulated. Prof. Dr. Markus Müschen from the University of California in San Francisco, USA, and his team worked together with the BIOSS researchers Prof. Dr. Hassan Jumaa and Prof. Dr. Michael Reth to find a new approach for treating the B-ALL tumour disease.



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Researchers discover new way to attract, kill pregnant malaria-transmitting mosquitoes

The battle against malaria is also a battle against its natural host, the mosquito, which means disrupting the insect's lifecycle is every bit as important as putting nets over beds. Now, an international research team has discovered what attracts mosquitos to lay their eggs in specific places.



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Markovian models show promise for describing postoperative pain trajectories

Markovian models show promise for describing postoperative pain states and, eventually, may help guide clinical decisions, a new study found.



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HSS study examines racial and socioeconomic disparities in hip fracture care

A study by researchers at Hospital for Special Surgery (HSS) finds that people in certain racial and socioeconomic groups are at a disadvantage when it comes to care they receive after fracturing a hip.



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Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

Mesenchymal stem cell (MSC) transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research.



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Use of balloon-expandable stent compared with medical therapy increases stroke risk

Among patients with symptomatic intracranial arterial stenosis (narrowing of an artery inside the brain), the use of a balloon-expandable stent compared with medical therapy (clopidogrel and aspirin) resulted in an increased of stroke or transient ischemic attack (TIA), according to a study in the March 24/31 issue of JAMA.



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New book focuses on life events resulting in teen motherhood

If Diane could reverse time, she never would have slammed the door--an act of teen frustration and ongoing family conflict that finally got her kicked out of her mother's house.



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Sympathetic nerve block showed no major benefit for PTSD in randomized controlled trial

A sympathetic nerve block that has shown promise for treatment of post-traumatic stress disorder (PTSD) performed no better than sham treatment in a randomized controlled trial, new research shows.



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Study: BPA can have adverse reproductive effects on humans

Bisphenol A (BPA) is a chemical that is used in a variety of consumer products, such as water bottles, dental composites and resins used to line metal food and beverage containers. Often, aquatic environments such as rivers and streams become reservoirs for contaminants, including BPA.



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AMGA, Avatar Solutions partner to provide patient satisfaction services

The American Medical Group Association today announced a partnership venture with Avatar Solutions to provide enhanced services for its Patient Satisfaction Benchmarking (PSAT) Program.



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Hip replacement procedure alleviates pain, improves function in young JIA patients

Hip replacement is often performed in patients with juvenile arthritis when their joints have been severely damaged by the disease.



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CMV-based vaccine provides long-lasting protective immunity against Ebola virus

A cytomegalovirus (CMV)-based vaccine provides long-lasting protective immunity against Ebola virus, and has potential for development as a disseminating vaccine strategy to prevent ebolavirus infection of wild African ape populations.



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DNA samples collected from tampons may help detect endometrial cancer

Researchers at Mayo Clinic have shown that it is possible to detect endometrial cancer using tumor DNA picked up by ordinary tampons. The new approach specifically examines DNA samples from vaginal secretions for the presence of chemical "off" switches — known as methylation — that can disable genes that normally keep cancer in check.



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Migraine headaches with auras may increase risk of stroke

People who suffer migraine headaches with auras are at roughly double the risk of suffering the most common type of stroke.



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Obesity, smoking, alcohol abuse, depressive disorders are risk factors for low back pain

New research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) identifies nicotine dependence, obesity, alcohol abuse and depressive disorders as risk factors for low back pain, a common condition causing disability, missed work, high medical costs and diminished life quality.



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Study confirms strong association between diabetes and later stage breast cancer

Diabetes is associated with more advanced stage breast cancer, according to a new study by the Institute for Clinical Evaluative Sciences (ICES) and Women's College Hospital.



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Omnicell to exhibit fully integrated medication management solutions at EAHP Congress

Omnicell, Inc., will exhibit the integration of its automated medication cabinets with MACH4's modular robotic solutions at the European Association of Hospital Pharmacists (EAHP) 25-27 March.



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Biological clue could help explain why some drinkers can't resist alcohol

Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not.



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Norovirus vaccine may be available in the future

A multivalent candidate vaccine elicits broad antibody responses to a range of norovirus strains, including strains not included in the vaccine or previously encountered by participants, according to a new study published this week in PLOS Medicine.



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Study: 53% of parents/caregivers of youth baseball pitchers unaware of safe pitching practices

A new study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that 53 percent of the parents/caregivers of youth baseball pitchers are unaware of safe pitching practices designed to prevent overuse injuries—common tears or damage, most often to the elbow (ulnar collateral ligament) or shoulder—which can cause pain, lost play time and, if not treated appropriately, arthritis, deformity and disability.



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Shape-memory alloy wires to drive artificial hands

Engineers at Saarland University have taken a leaf out of nature's book by equipping an artificial hand with muscles made from shape-memory wire. The new technology enables the fabrication of flexible and lightweight robot hands for industrial applications and novel prosthetic devices.



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New medical journal launched by Mayo Clinic Center for Tuberculosis

The Mayo Clinic Center for Tuberculosis, a regional training and consultation center at Mayo Clinic's campus in Rochester, Minn, is today launching a new medical journal, the Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. The online journal is published by Elsevier.



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Brain-somatic-activating mutations in MTOR cause focal cortical dysplasia type II

Epilepsy is a brain disorder that afflicts more than 50 million people worldwide. Many epilepsy patients can control their symptoms through medication, but about 30% suffer from intractable epilepsy and are unable to manage the disease with drugs. Intractable epilepsy causes multiple seizures, permanent mental, physical, and developmental disabilities, and even death.



from The Medical News http://ift.tt/1CXnOe1

New research finds link between milk consumption and high levels of glutathione in the brain

New research conducted at the University of Kansas Medical Center has found a correlation between milk consumption and the levels of a naturally-occurring antioxidant called glutathione in the brain in older, healthy adults.



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FirstCare Health Plans receives three-year accreditation status from NCQA

FirstCare Health Plans announced today that it has earned three-year Accreditation status from the National Committee for Quality Assurance (NCQA).



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Experimental drug that attacks brain tumor cells passes early tests

An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.



from The Medical News http://ift.tt/1CXnLip

Jr. NBA and FrieslandCampina partnership promotes active lifestyle in South-East Asian children

FrieslandCampina and Jr. NBA today celebrate the first anniversary of their successful partnership designed to encourage an active lifestyle amongst children in South-East Asia.



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Boston Scientific announces successful implantations of WATCHMAN Device in three US patients

This week, three patients in the United States received the first implants of the Boston Scientific Corporation WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device.



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Omnicell receives notification from NASDAQ OMX Group for noncompliance with Nasdaq Listing Rule

As indicated in a Form 8-K filed with the SEC on March 20, 2015, Omnicell, Inc. received a written notification from the NASDAQ OMX Group, Inc. on March 18, 2015, indicating that the Company was not in compliance with Nasdaq Listing Rule 5250(c)(1) for continued listing, due to the delay in filing its Annual Report on Form 10-K for the period ended December 31, 2014 beyond the extended filing due date of March 17, 2015.



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2015 Minds Matter event raises funds to support brain tumor research

One day in 2009, Maria Nijim's father got behind the wheel of his car and realized he couldn't see out of one eye. An MRI showed a tumor and then surgery confirmed a devastating diagnosis – glioblastoma – the most aggressive type of brain tumor.



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BIO KOREA celebrates 10th anniversary to share new information and technology in health industry

BIO KOREA is celebrating its 10th anniversary as a convention to share the latest information and technology in the health industry and to establish corporate partnerships among global experts.



from The Medical News http://ift.tt/1Bl6GJd

DePuy Synthes Companies offers new software solutions to optimize care for orthopaedic patients

DePuy Synthes Companies is offering health care professionals a new way to track and analyze patient data in real-time and a new program to improve patients' experience with joint replacement surgery.



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Mexican researcher close to finding a cure for Parkinson's disease

Parkinson's disease, which took world fame after being diagnosed in various personalities such as actor Michael J. Fox, the heavyweight champion Muhammad Ali and the painter Salvador Dalí, could be very close to a cure, thanks to a Mexican researcher which managed to eliminate its neurological effects with an immunosuppressant.



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Study finds clustered cardiometabolic risk factors in children

Lifestyle-related cardiometabolic risk factors cluster already in children in the same way as in adults, according to research from the University of Eastern Finland. A cardiometabolic risk score was used to evaluate cardiometabolic risk in different age groups.



from The Medical News http://ift.tt/1LVM6cJ

Greatist Workout of the Day: Wednesday, March 25th



This series of GWODs was designed exclusively for Greatist by Bodeefit. For more information about the exercises in this workout, or to see video demos of each movement, follow the links below the graphic. Be sure to note the results of your workout so you can track your progress as you go.


Before you tackle this workout, try this quick and effective full-body warm-up. It's just five simple moves but hits every major muscle group and gets your heart pumping.


Greatist Workout of the Day March 25

The Kemper


Complete as many rounds of the following as safely possible in 20 minutes.


10 Step-Ups

30-second Wall Sit

10 Lateral Burpees


Want to kick up the intensity? Hold a medium weight dumbbell or kettlebell in front of your chest during the wall sit. And don't forget to check back tomorrow for a totally new (but equally awesome) GWOD!








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Duke researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus (HPV), the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed.



from The Medical News http://ift.tt/1GSOnic

First randomized, controlled trial of pharmacotherapy in PCD patients now in place

Primary ciliary dyskinesia (PCD) is a rare, genetic respiratory tract disorder leading to progressive pulmonary dysfunction. It exhibits many problems typical for orphan diseases: delayed diagnosis, limited evidence-based knowledge etc. The European Union is funding BESTCILIA (Better Experimental Screening and Treatment for Primary Ciliary Dyskinesia) to introduce uniform guidelines for PCD treatment and diagnosis across Europe.



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Non-invasive imaging tests may predict healthy adults' future risk of heart attack, stroke or death

Adding two non-invasive imaging tests to traditional cardiovascular disease risk factor assessment more precisely predicts a healthy patient's future risk of heart attack, stroke, or premature death, according to a study led by Icahn School of Medicine at Mount Sinai and published in the March 24 edition of the Journal of the American College of Cardiology.



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Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Kidney transplantation outcomes from deceased African-American donors may improve through rapid testing for apolipoprotein L1 gene (APOL1) renal risk variants at the time of organ recovery, according to a new study led by researchers at Wake Forest Baptist Medical Center.



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New imaging technique could give precise information about structures inside tissues, cells

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, thanks to an imaging technique developed by University of Illinois researchers and clinical partners.



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Discovery opens door to possible new ways to break transmission cycle of schistosomiasis

Researchers at Oregon State University have discovered a group of genes in one species of snail that provide a natural resistance to the flatworm parasite that causes schistosomiasis, and opens the door to possible new drugs or ways to break the transmission cycle of this debilitating disease.



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Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

The newest gene editing tool - called CRISPR-Cas9 - is leading to new research possibilities in cell biology and neuroscience. This includes the ability to make transgenic animal models more quickly, which helps researchers better study diseases that affect thousands of people each year.



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University of Michigan scientists grow first 3D mini lungs from human stem cells

Scientists from the University of Michigan have grown the first 3D mini lungs from stem cells. The study, published in eLife, compliments other developments in the field such as growing mainly 2D structures and building lung tissue from the scaffold of donated organs.



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Cancer Research UK, EPSRC partner to fund multidisciplinary cancer research projects

Cancer Research UK has partnered with the Engineering and Physical Sciences Research Council, to co-fund multidisciplinary research projects.



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New research shows spinal surgery improves sexual function, reduces low back pain

Chronic low back pain can limit everyday activities, including sex. New research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), found that 70 percent of patients consider sexual activity "relevant" to their life quality, and patients who receive surgical treatment for spinal spondylolisthesis (DS) and spinal stenosis (SS)--common degenerative conditions most often occurring in older adults--were twice as likely to report no pain during sex.



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ItpkB enzyme regulates stem cells function to prevent cancer, anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time--and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations.



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Loyola ophthalmologist recommends specific foods and supplements for healthy vision

You may remember your mother telling you to eat your carrots; they are good for your eyes. Well, she was right. "Carrots are actually just one of the many foods, and supplements that contribute to good eye health," says James McDonnell, MD, pediatric ophthalmologist, Loyola University Health System. "In some cases, eyesight can actually be improved depending on what you eat."



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Patients with carpal tunnel syndrome twice as likely to have migraine headaches, shows study

Patients with carpal tunnel syndrome are more than twice as likely to have migraine headaches, reports a study in Plastic and Reconstructive Surgery--Global Open, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS).



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Newly discovered bodily process may explain fetal brain bleeds

A newly discovered bodily process in mice may explain why some human fetuses who have different antigens than their mothers suffer life-threatening brain bleeds, according to a new study.



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People who take many doses are more likely to crush tablets, reduce their effectiveness

People who take more than four doses of medicine a day appear more likely to crush tablets or open capsules potentially reducing their effectiveness, QUT research has found.



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Cancer-specific mortality lower in Asian Americans than non-Hispanic whites, shows study

Numerous studies have documented racial differences in deaths from cancer among non-Hispanic whites and African Americans, but little has been known about survival outcomes for Asian Americans who have been diagnosed with cancer, until now.



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Exercise and chronic fatigue syndrome: an interview with Professor Trudie Chalder

Chronic fatigue syndrome (CFS) is characterised primarily by fatigue but people often report muscle pain and sleep problems as well as concentration and memory problems. The symptoms affect people’s ability to carry out normal activities that healthy people take for granted. CFS can affect relationships, work and leisure activities.



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A new approach to TBI therapy

Innovative angles of attack in research that focus on how the human brain protects and repairs itself will help develop treatments for one of the most common, costly, deadly and scientifically frustrating medical conditions worldwide: traumatic brain injury.



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Researchers find protein Pom1 regulates different processes of cell growth and division

Investigators from Dartmouth's Norris Cotton Cancer Center led by James Moseley, PhD have found that the protein Pom1 possesses the ability to modify different sets of proteins to coordinate the processes of cell growth and division.



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Rigontec raises €4.8 million in second closing of Series A financing round

Rigontec GmbH, a privately held biopharmaceutical company developing RNA-based immunotherapeutics for the treatment of cancer and viral diseases, today announces it has raised €4.8 million in a second closing of its Series A financing round from Forbion Capital Partners, a Dutch life-sciences venture capital firm, and Sunstone Capital, a Copenhagen based venture capital investor.



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Researchers use genetic information to track the fatal spread of multidrug-resistant TB

Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK.



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Myriad announces Prolaris® test biopsy results from EMPATHY-P study at European Association of Urology annual meeting

Myriad Genetics, Inc. (NASDAQ: MYGN) today announced that results from the EMPATHY-P clinical study of Prolaris in patients newly diagnosed with prostate cancer will be highlighted at the 30th Annual Congress of the European Association of Urology.



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Strategies aimed at reducing childhood obesity should acknowledge individuals' rational taste preferences

Strategies aimed at reducing childhood obesity should acknowledge individuals' rational taste preferences and apply insights from behavioral economics to design choice architecture that increases their likelihood of success, say two physician-scientists from the Perelman School of Medicine at the University of Pennsylvania and the Center for Health Incentives and Behavioral Economics in an editorial published in JAMA Pediatrics.



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Researchers suggest genetic predisposition to spontaneous coronary artery disease

A Mayo Clinic study has identified a familial association in spontaneous coronary artery dissection, a type of heart attack that most commonly affects younger women, suggesting a genetic predisposition to the condition, researchers say.



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Birmingham academics educate Chinese grandparents to tackle childhood obesity

Academics from the University of Birmingham, UK are engaging with grandparents in China, to help tackle the increasing problem of obesity amongst Chinese children in a trailblazing public health programme.



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Plexin D1 gene determines body fat distribution in humans

Scientists have known for some time that people who carry a lot of weight around their bellies are more likely to develop diabetes and heart disease than those who have bigger hips and thighs.



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Maintaining heel-toe pattern while running barefoot may lead to frequent injuries in older athletes

In recent years there has been an explosion in barefoot running, as well as the purchase and use of "minimalist" running shoes that more closely resemble barefoot running by encouraging the balls of the feet, between the arch and toes, to hit the pavement first.



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Scientists use DNA sequencing to trace the spread of drug-resistant TB

Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK.



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Functional scores are higher in men before and after TKR surgery, shows study

While men and women have similar levels of improvement following total knee replacement (TKR) surgery, men have higher levels of function before and after TKR, according to new research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).



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Previous joint pain, diabetes and overall health status may predict arthritis pain

Diabetes and previous joint pain, along with a patient's overall physical health status, may predict arthritis pain with nearly 100 percent accuracy, in new research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).



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Bbisphosphonate treatment following distal radius fracture associated with atypical femur fractures

Osteoporosis is a disease of progressive bone loss affecting more than 44 million Americans and contributing to an estimated 2 million bone fractures each year.



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Arthritis Awareness Week capped off with amazing William's Walk event

Hundreds of people joined Arthritis & Osteoporosis NSW in walking Parramatta Park in aid of juvenile arthritis, a condition that is rarely discussed in the community. William’s Walk was crucial in getting the word out that juvenile arthritis affects 6000+ children throughout NSW, raising over $50,000 in the process.



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Most child pedestrian injuries occur near schools, bus stops, and in the spring months

New research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that most child pedestrian injuries involving a motor vehicle occurred while children were unsupervised, near schools and bus stops, and in the spring months during the afternoon and evening hours.



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Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Rochester, Minnesota, have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer's disease.



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Newly identified proteins could shed light on the mechanisms of ALS

Where ALS comes from and how it progresses are mysteries that continue to vex medical science. But recent research at Sweden's KTH Royal Institute of Technology has found three proteins that could shed some light on the mechanisms behind this deadly disease.



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New report highlights the need for disclosing Alzheimer's diagnosis to patients

The Alzheimer's Association's 2015 Alzheimer's Disease Facts and Figures report, released today, found that only 45 percent of people with Alzheimer's disease or their caregivers say they were told the diagnosis by their doctor.



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Greatist Workout of the Day: Tuesday, March 24th



This series of GWODs was designed exclusively for Greatist by Bodeefit. For more information about the exercises in this workout, or to see video demos of each movement, follow the links below the graphic. Be sure to note the results of your workout so you can track your progress as you go.


Before you tackle this workout, try this quick and effective full-body warm-up. It's just five simple moves but hits every major muscle group and gets your heart pumping.


Greatist Workout of the Day: March 24

Tabata Tuesday


Perform each movement for a total of 4 minutes, alternating between 20 seconds of all-out effort and 10 seconds of rest. The total length of the workout is 12 minutes.


Jumping Lunges

Sit-Ups

Mountain Climbers


Want to kick up the intensity? Hold lightweight dumbbells or kettlebells in both hands during the jumping lunges. And don't forget to check back tomorrow for a totally new (but equally awesome) GWOD!








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Study shows 80% of new general pediatricians are satisfied with their first jobs

Despite reports indicating job dissatisfaction among some physicians, at least one group of doctors seems to be starting their careers on the right note - pediatricians.



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Veeva Systems launches Veeva OpenKey at Eyeforpharma Barcelona 2015

On the opening day of eyeforpharma Barcelona 2015, Veeva Systems (NYSE: VEEV) announced Veeva OpenKey, a new approach to customer reference data for the life sciences industry.



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Inexperienced staff linked to ward suicides, finds mental health report

Suicidal patients who are under observation may be put at risk by relying on inexperienced staff and agency nurses, according to a new report issued today.



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Implementation of video-based decision aids influences care decisions in urology

After Group Health Cooperative implemented video-based decision aids for men with two common prostate conditions, rates of elective surgery for benign prostatic hyperplasia (BPH) and rates of active treatment for localized prostate cancer declined over six months.



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Publicly insured Americans who undergo lung transplantation fare worse than their UK counterparts

Publicly insured Americans who undergo lung transplantation for cystic fibrosis fare markedly worse in the long run than both publicly insured patients in the United Kingdom and privately insured Americans, according to the results of a study conducted by researchers from Johns Hopkins in Baltimore and U.K. colleagues working in that nation's government-funded National Health Service.



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Anorexics’ brains are wired differently, shows study

Researchers at the University of California, San Diego School of Medicine have pinpointed differences in brain function that may help to explain how people with anorexia nervosa can continue to starve themselves, even when already emaciated.



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Lean Six Sigma approach improves effectiveness and efficiency in hospital processes

Implementing a well-established business approach allowed physicians to shave hours off pediatric patient discharges without affecting readmission rates, according to researchers at Penn State Hershey Children's Hospital.



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Comprehensive medication assessment, monitoring plan needed to improve treatment for cancer patients

Open the medicine cabinet of a senior and you're likely to find scores of pill bottles. Physicians are often unaware of all the medications a patient is taking, which can result in unnecessary additional prescriptions, non-prescription medications and potential drug-drug interactions that cause unexpected adverse effects.



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Researchers and medical bodies explore ways to secure funds for womb cancer research

A national group of researchers, medical bodies and charities, led by The University of Manchester is looking for help in setting the top priorities for fighting womb cancer, with a survey launched today (23 March 2015).



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Nationwide survey helps formalize career path for advance practice RDNs

A nationwide survey of registered dietitian nutritionists (RDNs) is helping to formalize a career path for RDNs seeking more responsibility and autonomy as clinicians, according to a paper published in the Journal of the Academy of Nutrition and Dietetics.



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Harmful effects of smoking may be reflected in the facial movements of unborn babies

The harmful effects of smoking during pregnancy may be reflected in the facial movements of mothers' unborn babies, new research has suggested.



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Scientists identify key molecules that trigger immune system to fight tularemia

Research led by scientists at St. Jude Children's Research Hospital has identified key molecules that trigger the immune system to launch an attack on the bacterium that causes tularemia.



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Men who exercise more have better erectile and sexual function

Men who exercise more have better erectile and sexual function, regardless of race, according to a recent study published in the Journal of Sexual Medicine.



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Discontinuation of statin therapy may benefit patients with terminal illnesses

Discontinuing statin use in patients with late-stage cancer and other terminal illnesses may help improve patients' quality of life without causing other adverse health effects, according to a new study by led by researchers at the University of Colorado Anschutz Medical Campus and Duke University and funded by the National Institute of Nursing Research (NINR).



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Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Research results published in the Journal of Neurotrauma and conducted by the Walter Reed Army Institute of Research (WRAIR) as part of a collaboration with Concert Pharmaceuticals, Inc. showed that a novel deuterium-containing sigma-1 agonist invented at Concert, called C-10068, demonstrated anti-seizure and anti-inflammatory effects in a preclinical model of traumatic brain injury (TBI).



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Study highlights the treatable causes of cerebellar ataxias

No cures are possible for most patients who suffer debilitating movement disorders called cerebellar ataxias. But in a few of these disorders, patients can be effectively treated with regimens such as prescription drugs, high doses of vitamin E and gluten-free diets, according to a study in the journal Movement Disorders.



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Co-infection reduces severity of East Coast fever, can help curb human malaria

When calves are infected by two parasite species at the same time, one parasite renders the other far less deadly, according to a new study published in the current journal of Science Advances.



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Snake-like robots follow the lead of real sidewinder rattlesnakes

Researchers at Carnegie Mellon University who develop snake-like robots have picked up a few tricks from real sidewinder rattlesnakes on how to make rapid and even sharp turns with their undulating, modular device.



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