Upstate offers FDA-approved SMR TT metal back glenoid implant for shoulder replacements

A novel, implantable device that is less invasive and allows surgeons to perform the most challenging and complex shoulder replacements is now available at Upstate Medical University through the Upstate Bone and Joint Center.



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MHRA reclassifies Pfizer’s Nexium Control as an OTC treatment for heartburn

Pfizer is pleased to announce that the MHRA has approved the reclassification of the well-established proton pump inhibitor (PPI) Nexium Control (esomeprazole), making it available for consumers to purchase it without a prescription.



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Two researchers receive Charles Rodolphe Brupbacher Prize for Cancer Research

Researchers Irving L. Weissman and Joan Massagué have won this year's Charles Rodolphe Brupbacher Prize for Cancer Research: Weissman, from Stanford University, for his work on healthy and sick stem cells; Massagué, from Memorial Sloan Kettering Cancer Center in New York, for his research on metastatic spread.



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Stuart improves Tube Roller range for safer sample mixing in labs

Bibby Scientific Ltd announced today that Stuart, a leading UK manufacturer of laboratory benchtop equipment, has enhanced its Tube Roller range to include valuable new features for sample mixing, incorporating detachable roller tubes and removable side panels.



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Inhibition of SIRT1 protein may hold promise for treatment of metastatic Ewing sarcoma

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 (SIRT1) protein as a future treatment option for metastatic Ewing sarcoma. The results of the study were published in the journal Cancer Research.



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Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders.



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Study recommends normalizing blood pressure in pregnant women

Throughout her career in Canada and the UK, Dr. Laura Magee has taken a restrained approach to use of blood pressure-lowering medication in her pregnant patients, fearing that lowering pressure could reduce the flow of blood and vital nutrients to their babies.



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Survey shows that vast majority of US neurosurgeons participate in defensive medicine

More than three-fourths US neurosurgeons practice some form of defensive medicine--performing additional tests and procedures out of fear of malpractice lawsuits, reports a special article in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.



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Exposure to certain chemicals may lead to early menopause

Women who are exposed to certain chemicals are more likely to experience menopause at a younger age, according to a newly published study by a researcher from the University of Colorado School of Medicine at the Anschutz Medical Campus.



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Jersey Shore University Medical Center offers robotic-assisted laparoscopic sleeve gastrectomy

For many people, losing weight is a personal and ongoing battle. At the Center for Weight-Loss Surgery at Jersey Shore University Medical Center, new options are available for those making the life changing decision to lose weight, including minimally invasive techniques such as robotic-assisted laparoscopic sleeve gastrectomy.



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Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.



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Nanoscale DNA tool to detect molecular behavior

A complex interplay of molecular components governs almost all aspects of biological sciences - healthy organism development, disease progression, and drug efficacy are all dependent on the way life's molecules interact in the body. Understanding these bio-molecular interactions is critical for the discovery of new, more effective therapeutics and diagnostics to treat cancer and other diseases, but currently requires scientists to have access to expensive and elaborate laboratory equipment.



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Minority stress affects same-sex couples' stress levels, overall health

New research by Allen LeBlanc, Health Equity Institute Professor of Sociology at San Francisco State University, studies how minority stress -- which results from being stigmatized and disadvantaged in society -- affects same-sex couples' stress levels and overall health.



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MD Anderson and AstraZeneca to conduct multiple studies in ovarian, gynecologic cancers

The University of Texas MD Anderson Cancer Center and AstraZeneca today announced a multiyear strategic research collaboration to conduct multiple, parallel clinical and clinically related studies in ovarian and other gynecologic cancers with the aim of improving patient outcomes.



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Blood tests for Chikungunya virus and rheumatoid arthritis could produce similar results

A mosquito-borne virus that has spread to the Caribbean and Central and South America and has caused isolated infections in Florida often causes joint pain and swelling similar to that seen in patients with rheumatoid arthritis.



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NCCN commemorates 20 years of advancing high-quality, high-value cancer care

On January 31, 2015, the National Comprehensive Cancer Network celebrates its 20th anniversary. Originally announced as an alliance of 13 leading cancer centers in 1995, NCCN has grown to a network of 25 academic cancer centers; the NCCN mission as an alliance of leading academic cancer centers devoted to patient care, research, and education, is to improve the quality, effectiveness, and efficiency of cancer care so that patients can live better lives.



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Multiplexed testing for EGFR and ALK gene rearrangements may be cost-effective for NSCLC treatment

Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker-guided treatment is cost-effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.



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FDA’s approval of ibrutinib to treat Waldenstrom's macroglobulinemia receives praises from LLS

The U.S. Food and Drug Administration approval of ibrutinib (Imbruvica) to treat patients with Waldenstrom's macroglobulinemia(WM) is a significant advance for patients with this rare blood cancer.



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Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.



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TCGA researchers uncover differences between tumors with and without HPV infection

The study by The Cancer Genome Atlas (TCGA) researchers analyzed the genomes of 279 head and neck cancer tumors. They identified subtypes of head and neck cancer based on their genomic characteristics, changes in smoking-related tumors, as well as genomic differences in head and neck cancer tumors linked to HPV, the most commonly sexually transmitted disease in the United States.



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Rare respiratory virus could be linked to severe neurological illness in children

A cluster of children from Colorado in the USA have been treated for muscle weakness or paralysis that may be connected to a nationwide outbreak of a usually rare respiratory virus called enterovirus D68 (EV-D68), one of more than 100 non-polio enteroviruses.



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AbbVie releases Phase 3 results from all-oral OBV/PTV/r treatment for GT1b chronic HCV infection

AbbVie released top-line Phase 3 results for its investigational, all-oral, ribavirin (RBV)-free, two direct-acting antiviral treatment with ombitasvir/paritaprevir/ritonavir (OBV/PTV/r) in patients with genotype 1b (GT1b) chronic hepatitis C virus (HCV) infection in Japan.



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Temple University Hospital participating in trial to test vibrating capsule for chronic constipation treatment

Chronic constipation is a common problem that affects approximately 15 percent of the U.S. population, according to the American Gastroenterological Association. It can be painful and lead to a reduction in a patient's quality of life. Temple University Hospital is the only hospital in the Philadelphia region participating in a nationwide clinical trial to test an innovative, vibrating capsule for patients with chronic constipation.



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TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe.



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NSF awards grant for study on user-centered design framework for powered lower-extremity exoskeletons

It wasn't too long ago that the idea of a wearable robot that would lend its user increased mobility and strength seemed like the stuff of science fiction; indeed, films like Aliens and Iron Man, which featured characters wearing powered exoskeletons, incited the imaginations of many.



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Micromotor fueled by stomach acid effectively delivers gold nanoparticles

Researchers at the University of California, San Diego have shown that a micromotor fueled by stomach acid can take a bubble-powered ride inside a mouse. These tiny motors, each about one-fifth the width of a human hair, may someday offer a safer and more efficient way to deliver drugs or diagnose tumors.



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New insight on how naturally occurring mutations can be introduced into DNA

Scientists have shed light on how naturally occurring mutations can be introduced into our DNA.



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Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane.



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Researchers identify molecular mechanisms that can prevent blindness, promote recovery from stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor, Ernest C. and Yvette C. Villere Chair of Retinal Degeneration Research, and Director of the Neuroscience Center of Excellence at LSU Health New Orleans, has discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke.



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Researchers review positive and negative effects of mobile, interactive media use by children

Mobile devices are everywhere and children are using them more frequently at young ages. The impact these mobile devices are having on the development and behavior of children is still relatively unknown. In a commentary in the journal Pediatrics, researchers review the many types of interactive media available today and raise important questions regarding their use as educational tools, as well as their potential detrimental role in stunting the development of important tools for self-regulation.



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Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein.



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Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Pancreatic cancer is one of the deadliest forms of the disease. The American Cancer Society's most recent estimates for 2014 show that over 46,000 people will be diagnosed with pancreatic cancer and more than 39,000 will die from it. Now, research led by Timothy J. Yen, PhD, Professor at Fox Chase Cancer Center, reveals that one reason this deadly form of cancer can be so challenging to treat is because its cells have found a way to sidestep chemotherapy.



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Scientists identify strong link between beclin 1 gene and triple-negative breast cancer

UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer and a gene that regulates the body's natural cellular recycling process, called autophagy.



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Lifestyle tips to lower heart disease risks

With the arrival of American Heart Month in February, it's that time of the year to remind ourselves to take good care of our hearts.



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Shire announces FDA approval of Vyvanse Capsules for binge eating disorder

Shire plc announced today that the U.S. Food and Drug Administration approved Vyvanse (lisdexamfetamine dimesylate) Capsules (CII), the first and only medication for the treatment of moderate to severe binge eating disorder (B.E.D.) in adults, shown to significantly reduce the mean number of binge days per week.



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Good results with surgery for gynecomastia in bodybuilders

With attention to some unique patient characteristics, breast reduction surgery achieves good aesthetic outcomes in bodybuilders with gynecomastia--enlargement of the male breast, according to a new report.



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No Increase in Complications of Breast Reconstruction over Age 65

Older women don't have an increased overall risk of complications from breast reconstruction after mastectomy, reports a new article. "Older patients should be counseled that their age does not confer an increased risk of complications after implant-based post-mastectomy breast reconstruction," concludes the study.



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Mobile teledermoscopy for short-term monitoring of atypical moles

Allowing patients to use mobile devices to capture skin images appears to be a feasible and effective method for short-term monitoring of atypical nevi (moles), according to an article.



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Clinical Trials - What You Need to Know

Thousands of people take part in clinical trails for a variety of reasons every day. Some are looking for ways to manage their disease and get medications before they are released onto to the market, others are just hoping to make a difference and offer their time and body to enable researchers to come up with new medications, surgical procedures and more that can help those that need treatments that work.



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Genetic support for insulin system role in growth hormone response

Genetic determinants of insulin sensitivity are positively related to spontaneous growth and response to growth hormone treatment in children born small for gestational age, researchers have found.



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Many MEN1 tumour types found in children

Most tumour types reported in adult patients with multiple endocrine neoplasia Type-1 can be found in children with the condition, although rarely before the age of 10 years, shows a large study.



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Nomogram aids management of boys with constitutional delay in growth and puberty

A puberty nomogram is better than the classical criteria for identifying boys with constitutional delay in growth and puberty, report researchers.



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Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Research shows that postprandial glucagon levels increase over time in children with newly diagnosed Type 1 diabetes, and are associated with worsening glycaemic control, suggesting an adjunctive treatment approach.



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Childhood macroprolactinomas amenable to dopamine agonist treatment

Dopamine agonist treatment normalises prolactin levels in about three-quarters of children with macroprolactinomas, show findings from a large series.



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Prone position linked to epilepsy sudden death risk

Around three-quarters of patients who have a sudden unexpected death in epilepsy are found lying in the prone position, show meta-analysis findings.



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Atypical features common in bipolar disorder subtypes, associated with therapy

Atypical features are prevalent in all subtypes of bipolar disorder, a Chinese survey published in Neuroscience Bulletin, shows, and are associated with the use of antidepressant medication in patients with mixed stage and remission subtypes.



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Chronic pain common in affective disorders

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows.



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Up to 2 per cent of Germany's population is dependent on hypnotics

Every year, the statutory health insurance companies cover bills for some 230 million daily doses of benzodiazepines. Roughly the same amount again is prescribed in private prescriptions, but this figure is often not taken into consideration. The exact number of persons with benzodiazepine dependency is not known, but an estimated 128,000 to 1.6 million people in Germany are likely to be affected.



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HIV's persistent adaptability

The adaptability of pathogens is a great challenge to modern medicine, particularly the growing bacterial resistance to antibiotics. But other pathogens also possess the ability to adapt and render drugs powerless. Drug-resistant HIV viruses can spread rapidly. Only the continuous introduction of new drugs can stop the virus from getting the upper hand, scientists report.



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Financial incentives help pregnant women to quit smoking

Offering shopping vouchers to expectant mothers can be cost effective. Smoking in pregnancy is a leading preventable cause of maternal and neonatal illness and death in developed countries.



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OSTAR introduces Cellular TeleHealth Blood Pressure Monitoring System in North America

OSTAR Healthcare Technology, a Washington State Based TeleHealth Solutions company, announced the North American launch of yet another first in their Cellular TeleHealth Blood Pressure Monitoring System.



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New software analyzes human genomes faster than other available technologies

Investigators have developed an analysis 'pipeline' that slashes the time it takes to search a person's genome for disease-causing variations from weeks to hours.



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Can Lean Management improve hospitals?

Waiting times in hospital emergency departments could be cut with the introduction of Lean Management and Six Sigma techniques according to research.



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Why Does Your Body Slow Down When You Are on a Diet? And What Can You Do About This?

Your body has a built in survival mechanism to save calories. It will slow the body down in times of crisis or prolonged rest. This means it needs fewer calories and can be the ruin of many a great diet effort. This is predictable and thus can be compensated for.



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5 Steps To Weight Loss Success

Remember, all the tips and advice in the world will be meaningless unless you are willing to give them a try and stick with it. Drastic weight loss does not happen overnight which is one of the main reasons why folks fail to meet their goal because of the amount of time it takes to lose 30, 50, or even 80+ pounds. However if you are willing to change some of your current living habits, and truly stick with it for more than a month, then you will find that bad habits can be changed into ones that will have a positive impact on your health and your body.



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Sitting Around Eating Constantly Used to Be a Survival Strategy, This Is Now Killing Us, What Gives?

We evolved to survive. We need to eat to survive. Hunger is an inbuilt powerful biological urge to make us seek food. This carried a great survival advantage in the Stone Age. So how has it all gone a bit wrong?



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The Secret To Getting A Flat Stomach Fast

If you are like most of us, you are looking at yourself in the mirror wishing you had a flat stomach. When you don't carry around the extra flab, you feel healthier, more confident, and more energetic. In fact, your health risks climb right along with your waist measurement. High levels of belly fat are associated with heart disease, diabetes, cancer, and stroke. Another life fact about having a flat stomach is obese patients are 37 percent more likely to die from injuries sustained in a car accident. So we can see the incredible importance of having a flat stomach. Here's some advice on how to get a flat stomach fast.



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Shared symptoms of Chikungunya virus, rheumatoid arthritis may cloud diagnosis

A mosquito-borne virus that has spread to the Caribbean and Central and South America and has caused isolated infections in Florida often causes joint pain and swelling similar to that seen in patients with rheumatoid arthritis.



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New technologies to help patients with Parkinson's disease

New wearable sensor networks and mobile phone applications are being tested for their potential to monitor and manage patients with Parkinson’s disease. The research aim is the usage of low-cost wearable sensors that can continuously collect and process the accelerometry signals to automatically detect and quantify the symptoms of the patient. Once we this is done, the information is sent to hospital to generate a daily report that will alert the doctor in case of any outlier.



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Neuland Labs' revenues for third quarter of FY 2015 decrease 17% to $17.14 million

Neuland Laboratories Ltd., a pharmaceutical manufacturer providing active pharmaceutical ingredients (APIs), complex intermediates and custom manufacturing solutions services to customers located in 85 countries, today announced financial results for the third quarter of fiscal year (FY) 2015, ended December 31, 2014.



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Family Doctor Medical Clinic opens new paediatric treatment centre in Moscow

Family Doctor Medical Clinic ltd announces opening of new paediatric treatment facility in Moscow.



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Centura Health, DaVita HealthCare Partners jointly unveil FullWell

Centura Health and DaVita HealthCare Partners today unveiled FullWell, the brand name of the two partners' recently announced joint venture, a company that aims to bring greater value to health care and lower costs for consumers in Colorado and Kansas.



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ANI Pharmaceuticals launches Etodolac 300mg oral capsules

ANI Pharmaceuticals, Inc. today announced the launch of Etodolac 300mg oral capsules, indicated for use in the management of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and acute pain.



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Nuvo Research announces topline results from WF10 Phase 2 allergic rhinitis clinical trial

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of topical and immunology products, today announced the results of its 16-week, double-blind, placebo-controlled, Phase 2 clinical trial conducted in Germany to compare the safety and efficacy of WF10 and its main constituents (sodium chlorite and sodium chlorate) with saline in patients with refractory allergic rhinitis and to compare the safety and efficacy of WF10 and its main constituents.



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Researchers identify molecular pathways that could lead to new therapeutic targets for cerebral malaria

A drug already approved for treating other diseases may be useful as a treatment for cerebral malaria, according to researchers at Harvard T. H. Chan School of Public Health. They discovered a novel link between food intake during the early stages of infection and the outcome of the disease, identifying two molecular pathways that could serve as new targets for treatment.



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Research shows effectiveness of Tamiflu

Earlier this month, the Centers for Disease Control and Prevention recommended the use of antiviral drugs to help treat influenza, in a year when the available vaccine is not a good match for the current strain.



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Totality of trials data confirm Tamiflu reduces length of symptoms, complications, and hospital admissions from influenza

The most thorough analysis of oseltamivir (marketed as Tamiflu) data to date, including all available published and unpublished randomised treatment trials of adults, suggests that the antiviral drug shortens the duration of flu symptoms by about a day, compared to placebo, in adults with laboratory-confirmed influenza.



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K. Hovnanian Children's Hospital introduces Meridian Dentistry for Children

K. Hovnanian Children's Hospital at Jersey Shore University Medical Center introduces Meridian Dentistry for Children, a specialized, full-service, dental practice for infants, children and adolescents in a child-friendly, caring environment.



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Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths.



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Researchers move one step closer to treating diabetes with human probiotic pill

Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research.



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Texting better than apps to treat people with mental illness

Texting may be a more suitable treatment aid for those with mental illness than mobile applications.



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UAB doctor says measles can be halted with safe, effective measles vaccine

An ongoing, multistate measles outbreak linked to a California amusement park has already caused 68 confirmed cases between Jan. 1 and 23, according to the Centers for Disease Control and Prevention.



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Menopause does not exacerbate or cause sleep problems, shows study

Women in their late thirties and forties who have trouble sleeping are more than three times more likely to suffer sleep problems during menopause than women who have an easier time getting shut-eye, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania.



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Negative communication between doctor and patient could make symptoms worse

Doctors who unintentionally communicate to patients that they don't believe or understand them could actually make symptoms worse, a new study suggests.



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Steroid use associated with five-fold increase of blood clots in IBD patients

Compared with biologic therapy, corticosteroid (steroid) use is associated with a nearly five-fold increase of venous thromboembolism in inflammatory bowel disease (IBD) patients, according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.



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Psychopath’s persistent violent behaviour associated with brain abnormalities

Psychopathic violent offenders have abnormalities in the parts of the brain related to learning from punishment, according to an MRI study led by Sheilagh Hodgins and Nigel Blackwood. "One in five violent offenders is a psychopath.



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Leading academics underscore the importance of diet and nutrition for mental Health

Evidence is rapidly growing showing vital relationships between both diet quality and potential nutritional deficiencies and mental health, a new international collaboration led by the University of Melbourne and Deakin University has revealed.



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Techne’s new qPCR system offers greater accuracy and higher quality data

Bibby Scientific Ltd announced today thatTechne®, a leading UK manufacturer of laboratory benchtop equipment, has launched its revolutionary new qPCR system, the Prime Pro 48.



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TxCell receives milestone payment of EUR 1 million concerning Ovasave collaboration, license agreement from Trizell

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T-cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today the receipt of the latest milestone payment of EUR 1 million from the Ovasave collaboration option, development and license agreement from Trizell (Trizell Holding SA).



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AstraZeneca announces research collaborations to use genome-editing tool for drug discovery and development

AstraZeneca today announced four research collaborations aimed at harnessing the power of CRISPR, a pioneering genome-editing technique, across its entire discovery platform in the company’s key therapeutic areas.



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Fujian University of Traditional Chinese Medicine installs MILabs PET-SPECT-CT preclinical imaging system

Fujian University of Traditional Chinese Medicine, in Fuzhou, China has installed a MILabs VECTor/CT system to boost their neurological research with preclinical Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT).



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Farnesoid-X receptor could play key role in hepatobiliary and gastrointestinal disorders

The farnesoid-X receptor (FXR), also known as the chief regulator of bile acid metabolism, is thought to play a role in some hepatobiliary and gastrointestinal disorders.



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Unique project launched to identify effects of exercise on young people's hearts

A unique research project to identify the effects of exercise on young hearts has been announced today.



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Research reveals key protein structure, paves way for better anti-anxiety drugs

When new medicines are invented, the drug may hit the intended target and nullify the symptoms, but nailing a bull's eye - one that produces zero side effects - can be quite elusive.



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Immunotherapy expert discusses the concept of precision immunology and personalized medicine

With President Obama's recent State of the Union speech addressing the launch of a national precision medicine initiative to further tackle cancer and other diseases, a leading immunotherapy expert from Rutgers Cancer Institute of New Jersey weighs in on where we stand with precision immunology and personalized medicine and what needs to be accomplished.



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Study: Common pesticide may alter the development of brain's dopamine system

A commonly used pesticide may alter the development of the brain's dopamine system -- responsible for emotional expression and cognitive function - and increase the risk of attention deficit hyperactivity disorder in children, according to a new Rutgers study.



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Study examines fear influenced colorectal cancer screening decisions in UK adults

People who worry about cancer are more likely to want to get screened for colon cancer, but feeling uncomfortable at the thought of cancer makes them less likely to actually go for the test, finds new UCL-led research.



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Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Immunomic Therapeutics, Inc. ("Immunomic Therapeutics"), a company developing next-generation vaccines based on the LAMP-vax platform, and Astellas Pharma Inc. ("Astellas") today announced they have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen.



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Neuroscientists propose new strategy for brain evolution

Little animations trying to master a computer game are teaching neuroscience researchers how the brain evolves when faced with difficult tasks.



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Support employees in Ontario vote to ratify agreement between OPSEU and Canadian Blood Services

Canadian Blood Services is pleased to announce that support employees in Ontario, represented by the Ontario Public Service Employees Union (OPSEU), have voted to ratify the agreement recently reached between the two parties.



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Older users of opioids more likely to become victim of homicide, shows study

Older users of opioids such as heroin are 27 times more likely to become a victim of homicide than the general population, a University of Manchester study of almost 200,000 users has found.



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Adropin hormone offers a promising treatment option for type 2 diabetes

In a study published in Molecular Metabolism, a SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes.



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Cardiologist promotes the importance of controlling high blood pressure

During Heart Month, the Cardiovascular Institute of New Jersey at Rutgers Robert Wood Johnson Medical School is promoting the importance of controlling high blood pressure, also called hypertension, in order to reduce the risk of coronary heart disease and other related chronic disorders in adults.



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What do medical journalists think about cancer research?

The intersection of medical journalism and cancer research has been the focus of recent study. Generally, journalists reported that they did not find pharmaceutical press releases to be helpful, preferring direct contact with physicians as their most reliable and prized sources of information.



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EKF Molecular Diagnostics collaborates with ANGLE for liquid biopsy development using Parsortix and PointMan technologies

EKF Molecular Diagnostics has agreed a collaboration with specialist medtech company ANGLE plc, to investigate the combination of ANGLE's Parsortix circulating tumour cell (CTC) harvesting platform with EKF Molecular's PointMan™ DNA enrichment technology as a liquid biopsy. If successful, the resulting simple blood test could enable the investigation of unexpected ultra-low level mutations in a patient's cancer for personalised cancer care.



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Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Park Systems, a leading manufacturer of atomic force microscopy (AFM) and nanoscale metrology products, proudly introduces Park NX-Bio, a powerful 3-in-1 bio-research tool that uniquely combines scanning ion conductance microscopy (SICM) with AFM and an inverted optical microscope (IOM) on the same platform.



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FDA approves first-of-kind device to treat obesity

The U.S. Food and Drug Administration has approved the Maestro Rechargeable System for certain obese adults, the first weight loss treatment device that targets the nerve pathway between the brain and the stomach that controls feelings of hunger and fullness.



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Texting may be more suitable than apps in treatment of mental illness

Texting may be a more suitable treatment aid for those with mental illness than mobile applications.This is the key finding of a new study led by researchers from Clemson University in collaboration with researchers from Indiana University and the Centerstone Research Institute. The study was published in the journal Personal and Ubiquitous Computing.



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Food and Emotion

Over the past ten years, I have had the honour of helping hundreds of men and women develop new healthy habits and improve their lives. When it comes to losing weight, improving performance or simply feeling better, improving the way we eat can be a great place to start. When I started, I thought nutrition was pretty simple: I could write up nutrition plans to achieve goals, or make simple swaps to effortlessly cut calories and increase satiety.



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Hair Care Tips - How to Care for Your Hair Extensions

Caring for hair extensions can be a bit of pain, but come to think of it, would you be happy with extensions that look good only about a month or so? Of course not. After you've forked out the cash to get hair extensions, it is necessary to have a proper hair care routine to maintain them so that they last for a long time. Taking care of hair extensions is an ongoing process, the results of which depend on you, your efforts and knowledge as well as your hair stylist. So, before you take the plunge, take a look at these helpful tips on hair extensions maintenance:



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Negative stereotyping affects memory and cognitive performance of older people

The most comprehensive analysis to date of research on the effect of negative stereotypes on older people's abilities has concluded that these stereotypes create a significant problem for that demographic.



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AP39 compound could help lower heart rate, blood pressure, and blood vessel stiffness

A gas that gives rotten eggs their distinctive odour could one day form the basis of new cardiovascular therapies.



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Weight Loss Resolution for 2015!

It is the New Year and you want to lose weight. So how do you make the dedication to health and weight loss without going overboard? There are a couple of ways. The first way is to plan your long term goal and break that down into small goals. The second way is to start small, take one step at a time and achieve that goal. Both ways are great and it really depends on your personality. Only you know which method suits you.



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Three Herbs for Faster Metabolism

Slow metabolism is such a pain in the butt. Even with a healthy diet, if body's metabolism is sluggish, we gain weight. Or at least that annoying extra weight just refuses to disappear.



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Scientists Have Invented A New Imaging System For Tumor Detection

Scientists have invented a unique imaging system that lights up tumors in the body when a laser is pointed at them. This invention will be instrumental in helping surgeons detect the cancerous region effectively during surgeries. Timely detection of the tumor may also help reduce the rate of recurrence of different forms of cancer.



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Top 5 Ways To Maintain Your Body Weight!

No matter how much you try to attract the opposite gender by your nature and character, you can't do so until you work hard on your body and turn externally attractive as well. There was a time when 'beauty with brains' could not be found; however, now you can find a lot of women who are not only intelligent, but also blessed with charm and beauty.



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Leveraging Internet of Things to Revolutionise the Healthcare Industry

With the emergence of IoT or Internet of Things, various technical gadgets have acquired precedence with connectivity and integration with each other. With a single connected family of products, even the healthcare industry can benefit tremendously in coming times.



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Sebacia reports positive clinical results from two independent studies in people with acne

Sebacia, Inc., a company dedicated to delivering breakthrough topical treatments to advance dermatology, has announced the presentation of positive clinical results from two independent studies conducted in Europeinvestigating the use of Sebacia gold microparticles to treat acne.



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DePuy Synthes Spine receives 510(k) clearance to market SYNAPSE OCT System with posterior cervical screws

DePuy Synthes Spine today announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its SYNAPSETM Occipital-Cervical-Thoracic (OCT) System with posterior cervical screws, the first time cervical screws have been indicated for use with a screw-rod posterior fixation system.



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4 Foods To Help You Boost Your Mood And Lose Weight

Do you know that you can boost your mood and at the same time lose weight by the food that you eat? Here are some of the best foods that you should eat in order to increase your mood and lose weight: Salmon - It contains omega-3-fatty acids that have been greatly associated with better moods. The fatty acids have also been linked to weight loss. Salmon has also been found to contain plenty of lean protein which makes you feel full for a long time thus you eat less. This plays a major role in helping you to lose weight.



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Marie Csete appointed president and chief scientist of HMRI

Huntington Medical Research Institutes, a leading biomedical research organization, has announced the appointment of Marie Csete, MD, PhD, its chief scientific officer, to her new role as president and chief scientist of HMRI.



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Quest Diagnostics, CDC partner to identify trends in diagnosis and treatment for viral hepatitis

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced that it will collaborate with the Centers for Disease Control and Prevention to identify trends in screening, diagnosis and treatment for four strains of viral hepatitis in the United States, based on insights revealed by analysis of Quest’s national testing database.



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Tracerco includes award-winning radiation monitors with PEDs to meet all radiation monitoring needs

Leading industrial technology specialist Tracerco, part of the Johnson Matthey group, has added to its range of award winning radiation monitors with a family of Personal Electronic Dosimeters (PEDs), providing a solution for every radiation monitoring need.



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People who carry gene variant associated with longevity have larger volumes in front part of brain

People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco.



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Finding could improve treatment, diagnosis of common reading disorders

A neuroimaging study by a University at Buffalo psychologist suggests that phonics, a method of learning to read using knowledge of word sounds, shouldn't be overlooked in favor of a whole-language technique that focuses on visually memorizing word patterns, a finding that could help improve treatment and diagnosis of common reading disorders such as dyslexia.



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OCC partners commend EU decision that supports disability protections for obesity

In a joint position statement, Obesity Care Continuum (OCC) partners agree with the premise behind a recent European Court of Justice ruling supporting disability protections for obesity under certain circumstances and call for these protections to be enacted in the United States.



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Respect for autonomy may positively impact parent-child relationships

Research shows that the quality of mother-child relationships greatly influences children's development socially, emotionally and academically.



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UCSD professor wins 2015 Japan Prize

Theodore Friedmann, MD, professor in the Department of Pediatrics at University of California, San Diego School of Medicine was named today one of three recipients of the 2015 Japan Prize, a prestigious international award honoring laureates whose "original and outstanding achievements in science and technology have advanced the frontiers of knowledge and served the cause of peace and prosperity for mankind.



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Loyola psychiatrist offers tips to cope with football withdrawal symptoms

When the football seasons with the final play of Sunday's Super Bowl, some fans may begin to feel withdrawal symptoms.



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Young Researcher's Meeting on Primary Ciliary Dyskinesia to be held in Bern, Switzerland

Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous disorder that affects approximately 1 in 20,000 individuals.



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Clear and concise communication essential to quality patient care in ED

The high-risk, rapidly changing nature of hospital Emergency Departments creates an environment where stress levels and staff burnout rates are high, but researchers at St. Michael's Hospital have identified the secret sauce that helps many emergency clinicians flourish - communication.



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Day-to-day chemical exposures linked to earlier menopause

Women whose bodies have high levels of chemicals found in plastics, personal-care products, common household items and the environment experience menopause two to four years earlier than women with lower levels of these chemicals, according to a new study at Washington University School of Medicine in St. Louis.



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Researchers receive DoD grant to develop new therapy against nerve agent exposure

University of Nebraska Medical Center researchers have received a $1.9 million grant from the Defense Threat Reduction Agency of the U.S. Department of Defense to develop a new therapy to protect military members from nerve agent exposure.



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3D printing technology can make heart surgery safer for children with congenital anomaly

Three-dimensional printing technology can make surgery safer for children with congenital heart disease and reduce the duration as well as the number of invasive procedures required.



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Online social connectedness promotes weight loss, shows study

If you want to lose pounds using an online weight management program, don't be a wallflower. A new Northwestern University study shows that online dieters with high social embeddedness -- who logged in regularly, recorded their weigh-ins and 'friended' other members -- lost more than 8 percent of their body weight in six months.



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electroCore’s non-invasive vagus nerve stimulation therapy safe, effective across a variety of conditions

Non-invasive vagus nerve stimulation (nVNS) ‘improves the safety and tolerability of VNS making it more accessible and facilitating further investigations across a wide range of uses when compared with surgically implanted VNS’ according to a review in the European Journal of Neurology.



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Scientists publish catalog of genetic mutations found in head and neck cancers

Scientists have published the first comprehensive catalog of genetic mutations and other abnormal changes found in 279 cancers of the head and neck, and have identified several broken molecular pathways that might be targeted by existing and future cancer drugs.



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Study: Green tea compound may activate a cycle that kills oral cancer cells

A compound found in green tea may trigger a cycle that kills oral cancer cells while leaving healthy cells alone, according to Penn State food scientists. The research could lead to treatments for oral cancer, as well as other types of cancer.



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GW Cancer Institute selected to study health disparities in cancer care

The George Washington University Cancer Institute received a $97K grant from Genentech to address health disparities in cancer care.



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CUMC evaluates impact, cost-effectiveness of implementing new hypertension guidelines

Full implementation of new hypertension guidelines could prevent 56,000 cardiovascular disease events (mostly heart attacks and strokes) and 13,000 deaths each year, without increasing overall health care costs, an analysis conducted by researchers at Columbia University Medical Center found.



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Researchers discover novel compound that helps curtail progression of temporal lobe epilepsy

Researchers at the LSU Health New Orleans Neuroscience Center of Excellence have found that a novel compound they discovered helps curtail the onset and progression of temporal lobe epilepsy.



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Maternal exposure to flame-retardants may contribute to preterm births

Researchers at The University of Texas Medical Branch have determined that maternal exposure to high levels of flame-retardants may be a contributing factor in preterm births.



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Researchers one step closer to identifying how lung cancer cells metastasize

Smoking is the leading cause of lung cancer, and it is estimated that more than 159,000 people in the United States died from the disease last year. Most of these deaths were because the cancer had spread to other organ sites. Following their recent discovery of a protein pathway, Moffitt Cancer Center researchers are one step closer to understanding how lung cancer cells metastasize.



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EGFR–TKI response worse in NSCLC patients with rare EGFR mutations

In patients with non-small-cell lung cancer, rare epidermal growth factor receptor mutations are associated with a poorer response to EGFR–tyrosine kinase inhibitors compared with frequently occurring ones, according to a study published in Lung Cancer.



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Chemotherapy plus radiation improves survival in R1 NSCLC patients

US researchers have identified a survival benefit of postoperative combination chemotherapy and radiation treatment in patients with non-small-cell lung cancer who have microscopically positive surgical margins, regardless of pathological stage.



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Age and HBsAg level predict NA-induced HBeAg seroconversion durability

The combination of age and baseline hepatitis B s-antigen level can help predict hepatitis B virus relapse in patients who achieve hepatitis B e-antigen loss or seroconversion following nucleos(t)ide analogue (NA) treatment, researchers report.



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Tenofovir stems treatment-induced kidney toxicity in HBV-related chronic hepatitis

Switching to tenofovir may stave further kidney and bone impairment in patients with hepatitis B virus-related chronic hepatitis taking adefovir-based therapy, retrospective study findings suggest.



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Long-term TDF therapy offers sustained HBV suppression without resistance

Patients with chronic hepatitis B virus infection can achieve sustained viral suppression with long-term tenofovir disoproxil fumarate treatment without developing resistance, shows a 7-year study.



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Promising results for stem cell therapy in MS

Preliminary findings suggest that nonmyeloablative haematopoietic stem cell transplantation may arrest, or even reverse, the progress of disease among patients with relapsing–remitting multiple sclerosis.



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Alectinib active against leptomeningeal metastases in ALK-positive NSCLC

Patients with anaplastic lymphoma kinase-rearranged non-small-cell lung cancer who have leptomeningeal metastases may benefit from treatment with the second-generation ALK inhibitor alectinib, a case series suggests.



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VATS lobectomy best for NSCLC patient short-term outcomes

Video-assisted thoracoscopic surgery lobectomy offers better short-term outcomes for patients with early-stage non-small-cell lung cancer than open lobectomy, multi-institutional research confirms.



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Plasma EGFR mutation cfDNA predicts advanced lung cancer outcome

Monitoring plasma cell-free DNA levels of epidermal growth factor receptor mutations may indicate prognosis for patients with lung adenocarcinoma after EGFR–tyrosine kinase inhibitor therapy, research suggests.



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SRS fails to improve survival for NSCLC brain metastases patients

Phase III trial findings suggest that carrying out stereotactic radiosurgery before chemotherapy does not improve overall survival for non-small-cell lung cancer patients with asymptomatic brain metastases compared with chemotherapy alone.



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Novel radioguided brain surgery technique could help pinpoint cancerous tissue

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.



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Incisional hernia repairs among older men rose 24. 2 percent from 2001 to 2010

Incisional hernia repairs among men age 65 years and older rose 24.2 percent in the United States from 2001 to 2010, according to a study. "The rising rates of emergent incisional hernia repair are troublesome due to the significantly increased risk of morbidity and mortality associated with the procedure," said the ead author of the study. "While many factors play into this mortality risk, it is most likely associated with increasing prevalence of abdominal surgeries, older age and its associated conditions or diseases."



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Dieters Beware! It's the Silly Season for Fad Diets

Every January, we are besieged with fake and exaggerated diet claims promising to let us lose lots of weight very quickly. Why do so many people fall for this? More importantly, what should one look to avoid if he or she has decided to shed a few pounds - and truly wishes to be successful?



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Top 7 Reasons To Use Botox To Look Younger!

You work hard at the gym almost every day to stay in shape, even after giving birth to your second or third child; you make sure that you keep some amount of money separately for the sake of buying cosmetics and other such stuff to hide your 'aging process'; you go to office and try to earn as much as you can so that you can buy different clothes for yourself to look beautiful or 'hot' on the streets. However, there's something for which you can't do anything all by yourself and that is those wrinkles that depict your true age.



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Top 7 Natural Ways to Get Rid of High Cholesterol!

You have suddenly started finding it difficult to walk for more than fifteen minutes; whenever you climb up the stairs, you start perspiring or fighting for air; you have not been spending sufficient time on working out for the sake of your body; you have absolutely no control on your diet and there's nothing that you can do to get rid of the growing fats of your body, because you have to spend more than nine hours at the office, sitting right in front of the computer screen to work. If you are going through the above mentioned...



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5 Reasons to Use Ayurvedic Treatment for Piles

I know how difficult it is to control the pain 'down there' when you have piles. Some people make fun of such health related issues, but they don't know the seriousness of the same. No matter what you do or how hard you try, it is not very easy to get rid of this problem. Piles can make you go through nightmares, especially when you want to have a 'clean' stomach, but are unable to do so. Moreover, you end up being frustrated, irritated and even depressed when you have piles.



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5 Reasons To GO NATURAL This Year!

No matter how much we humans advance in our lives, deep down inside we all know about the various benefits of being natural. I completely agree with the fact that allopathic medicines give you quick relief from the health related issues that you are going through, but it is also a proven fact that such medicines do not go to the roots of the problems.



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Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

In a new research study, scientists from Vision Genomics, LLC, Insilico Medicine, Inc., and Howard University showed that Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) is comparable to normal aging with respect to cellular signaling pathways, and that HGPS truly recapitulates the normal aging process.



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Silencing neurons in the arcopallium

New research published by the Neuronal Mechanism for Critical Period Unit at the Okinawa Institute of Science and Technology Graduate University has shown the effectiveness of chemogenetic inhibition used to suppress neuronal activity as well as interesting results on how vocalization is controlled through this techniques application in zebra finches.



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Infants show consistent patterns of brain activity in response to painful vaccinations

Infants show distinct, consistent patterns of brain activity in response to painful vaccinations, reports a study in the February issue of PAIN, the official publication of the International Association for the Study of Pain.



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Lund researchers find new way to identify malignant tumours in children

A research group at Lund University in Sweden has found a new way to identify the most malignant tumours in children. The method involves studying genetic 'micro-variation', rather than the presence of individual mutations.



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Combating pre-pregnancy obesity helps both mother and child

Before a woman gets pregnant it is very common for her to plan and prepare for her child's arrival to ensure that the baby will benefit from the healthiest, most comfortable life possible. Sometimes, these preparations may be financial or they may involve taking such important healthcare steps as quitting smoking. Now, according to data from the Swedish Medical Birth Register, one of the best things that a mother can do for the health of her child is to ensure that she is at a healthy weight.



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Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Treating travellers' diarrhoea with antibiotics can promote the spread of drug-resistant "super-bacteria".



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Improving prefrontal cortex activity could help autistic people regulate emotions

Tantrums, irritability, self-injury, depression, anxiety. These symptoms are associated with autism, but they're not considered core symptoms of the disorder. Researchers from the UNC School of Medicine are challenging this assertion. They have used functional MRI to show that - when it comes to the ability to regulate emotions - brain activity in autistic people is significantly different than brain activity in people without autism.



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Study: Targeted biopsy technique better than standard biopsy at detecting high-risk prostate cancer

Among men undergoing biopsy for suspected prostate cancer, targeted magnetic resonance/ultrasound fusion biopsy, compared with a standard biopsy technique, was associated with increased detection of high-risk prostate cancer and decreased detection of low-risk prostate cancer, according to a study in the January 27 issue of JAMA.



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Lung Cancer Clues Found In Downstream Pathway

Despite the promise of the gene KRAS as a target for treating lung cancer, finding effective therapies has been challenging. Now researchers are traveling down the pathway to find what makes KRAS cancerous.



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UofL study investigates safety, effectiveness of EBV for treating emphysema symptoms

The University of Louisville has launched a research trial to study an investigational medical device designed to aid patients with emphysema by shutting off the diseased part of the lung. UofL is the only site in Kentucky among 14 nationwide testing the device.



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Study finds that African-American people with colon cancer have lower survival rates

African-American people diagnosed with colon cancer have consistently lower survival rates compared with white patients, despite a nationwide decline in colon cancer deaths overall.



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Study provides new route for treating patients with difficult-to-treat Parkinson's symptoms

Parkinson's disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment.



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Developmental salivary biomarkers linked to feeding success in newborns

Results from a study published online in the Journal of Pediatrics hold the potential to substantially improve clinical decision-making to determine when a premature newborn is ready for oral feeding. The study describes developmental salivary biomarkers associated with feeding success in newborns, markers that could lead to development of objective assessment tools for caregivers.



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Ghrelin hormone supplement increases sexual activity in mice

Swedish studies show that mice that receive a supplement of the "appetite hormone" ghrelin increase their sexual activity. Whether the hormone has the same impact on humans is unknown - but if it does, the researchers may have found the key to future treatments for sex abuse.



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Research explores effect of DBS treatments in animals with brain injuries

The research, published in Behavioural Brain Research, was conducted by Pilar Segura and Ignacio Morgado (coordinators), Laura Aldavert and Marc Ramoneda, psychobiologists of the Institute of Neurosciences and the Department of Psychobiology and Health Sciences Methodology of the UAB and by Elisabet Kadar and Gemma Huguet, molecular biologists of the University of Girona, to explore the power of Deep Brain Stimulation treatments in the hypothalamus to recover the ability to learn and remember after a severe lesion of the amygdala.



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Investigators make medical breakthrough in repairing tracheal damage

Investigators at The Feinstein Institute for Medical Research have made a medical breakthrough using 3D printing on a MakerBot Replicator 2X Experimental 3D Printer to create cartilage designed for tracheal repair or replacement.



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Novel technique could help identify cancerous tissue during brain tumor surgery

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.



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Doctoral thesis finds how parental time pressure leads to mental health problems among children

A doctor's thesis at Sahlgrenska Academy has found that children whose parents experience time pressure are more likely to have mental health problems.



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TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.



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Study finds no evidence that testosterone replacement therapy increases cardiovascular risk

Fears of a link between testosterone replacement therapy and cardiovascular risk are misplaced, according to a review published in this month's Mayo Clinic Proceedings. The therapy has come under widespread scrutiny in recent months, including by a federal Food and Drug Administration panel convened last fall.



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Plymouth researchers awarded grant to evaluate pulmonary rehabilitation programme in East Africa

Chronic lung disease is a growing and debilitating health issue for countries in East Africa. Resulting from respiratory infections such as TB and HIV, and lifestyle problems such as tobacco smoking and poor nutrition, chronic lung disease affects one in five adults in Africa and is a major threat to health.



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Androgen receptor in prostate cancer cells can activate different gene set when bound to antiandrogens

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.



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New survey finds long-term benefits of brain surgery in patients with epilepsy

Brain surgery for otherwise hard-to-treat epilepsy is effective for up to 15 years, according to a new survey by Henry Ford Hospital physicians.



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Study sheds new light on nighttime leg cramps

Nighttime leg cramps commonly affect adults over the age of 50, but are also known to occur in younger adults and children. While their cause is unknown, a study from the University of Alberta's Faculty of Medicine & Dentistry is shedding new light on the painful condition.



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Low staff vaccination rates put vulnerable populations at risk of getting influenza

Influenza is associated with as many as 7,300 deaths annually in nursing home residents, but the vaccination rate for nursing home staff is only 54 percent, according to a study in the February issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology.



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Researchers devise novel way to generate corneal stem cells for treating corneal blindness

Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness.



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Study links lysosomal dysfunction with neonatal intestinal disorders

Neonatal intestinal disorders that prevent infants from getting the nutrients they need may be caused by defects in the lysosomal system that occur before weaning, according to a new Northwestern Medicine study.



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Purdue University researchers find promising way to treat late-stage prostate cancer

Low doses of metformin, a widely used diabetes medication, and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue University study finds.



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Common treatment not effective in reducing risk of death for patients with TBI

More than 1.7 million people in the U.S. alone suffer a traumatic brain injury (TBI) every year, often resulting in permanent disabilities or death. Up to half of these patients will experience progression of bleeding inside or around the brain, the occurrence of which is associated with an increased risk of death.



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Sanford-Burnham researchers use human pluripotent stem cells to grow new hair

In a new study from Sanford-Burnham Medical Research Institute, researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss.



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Georgia Tech researchers unveil new version of genome annotation system

Georgia Tech researchers, working with colleagues in the National Center for Biotechnology Information, have released a new version of a genome annotation system capable of analyzing more than 2,000 prokaryotic genomes per day, helping researchers accelerate prokaryotic genomics-based studies worldwide.



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Listeria poses pregnancy risk

A gut bacterium called Listeria (Listeria monocytogenes), which is often found in soft cheese, is known to present a risk to pregnant women. Listeria uses distinct tactics to breach the intestine and the placenta, using a protein called phosphoinositide-3 kinase (PI3-K), according to a study published in The Journal of Experimental Medicine.



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Yale researcher receives 2015 Frontiers of Knowledge Award in Biomedicine

A Spanish foundation has awarded a major scientific prize to Yale researcher Joseph Schlessinger and two colleagues in recognition of their work leading to the first personalized treatments for cancer. The 2015 Frontiers of Knowledge Award in Biomedicine from the Madrid-based BBVA Foundation includes a €400,000 cash prize.



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Case Western researchers awarded NSF grant to develop new method to reduce risk of Ebola virus

Health care workers must diagnose and isolate Ebola victims at an early stage to have a chance to save them and prevent the virus from spreading. But the most sensitive and quickest diagnostic test produces a small percentage of false negative results that undermine efforts to control the deadly agent.



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UNC researchers discover how two genes interact to trigger worst form of ovarian cancer

In the battle against ovarian cancer, UNC School of Medicine researchers have created the first mouse model of the worst form of the disease and found a potential route to better treatments and much-needed diagnostic screens.



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Medco Health develops online monitoring system for people with sleep apnoea-hypopnoea syndrome

The company Medco Health at the Business, Scientific and Technological Park, Espaitec, of the Universitat Jaume I of Castellón, has developed an assistance system based on telemedicine using information and communication technologies, which allows an online daily monitoring of people with sleep apnoea-hypopnoea syndrome.



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Genevac's new SampleGenie 4 for direct concentration of large sample volumes into vials

SampleGenie 4 is the latest version of Genevac’s unique technology for direct concentration of large sample volumes into vials, designed for use in the Rocket Synergy Evaporator.



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Biolin Scientific acquires the key patent protecting multi-hole, high-throughput ion channel screening

Biolin Scientific today announces the acquisition of a key patent related to performing multi-hole, high-throughput ion channel screening.



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Bronchial thermoplasty for severe asthma: an interview with Dr. Rob Niven

Internationally, severe asthma is defined as anybody who is on maximum therapy, which has no measurable side effects, but still have symptoms of persistent asthma. In the UK, that effectively means people who require oral steroids for their asthma two or more times a year.



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Forget the Magazine Covers: Your Weight Loss Plan Is Personal

Popular culture stresses quick fixes for weight loss and personal well-being. However, the process of losing weight is different for everyone, and should be approached from a personal perspective.



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Targeted MRI/ultrasound beats standard biopsy to detect high-risk prostate cancer

Targeted biopsy using new fusion technology that combines magnetic resonance imaging (MRI) with ultrasound is more effective than standard biopsy in detecting high-risk prostate cancer, according to a large-scale study.



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A Guide to Understanding Your Emergency Care Health Coverage

Health insurance is a lifesaver, but understanding all of your benefits and what emergency care will you cost you can be confusing. Luckily, there are a few easy questions you can ask your plan administrator to understand your health coverage, should you ever have to take a trip to the ER.



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Four Characteristics to Look for in a Quality Hospital

Whether you're visiting for a checkup or undergoing long-term treatment, the healthcare you receive is important. Examine a hospital to determine its quality and effectiveness.



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Negative patient-doctor communication could worsen symptoms

A type of 'nocebo' response -- where patients perceive a lack of understanding or acceptance from their doctor -- could create anger and distress, physiological conditions that could worsen illness, a new research shows.



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Web surfing to weigh up bariatric surgery options

Obese people considering weight-reducing surgery are only topped by pregnant women when it comes to how often they turn to the Internet for health advice. While most use it to read up on relevant procedures and experiences, some patients actually chooses a surgeon based solely on what they have gleaned from the web, a study concludes.



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Low sodium levels increases liver transplant survival benefit in the sickest patients

Researchers report that low levels of sodium in the blood, known as hyponatremia, increase the risk of dying for patients on the liver transplant waiting list. The study showed an increase in survival benefit for patients with hyponatremia and a Model for End Stage Liver Disease (MELD) score of 12 or more. The MELD score measures the risk of death on waiting list. It is calculated using patient’s serum bilirubin, creatinine, and prothrombin time and is used by national organ allocation policy to determine the priority for a patient on the transplant waitlist. Patients who are most sick, with a high MELD score, are at the top of the waitlist.



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Decisions on Future Childbearing in Women Diagnosed with a Meningioma

43% of surveyed female meningioma survivors aged 25–44 yrs stated they were warned that pregnancy was a risk factor for meningioma recurrence. Nevertheless, these women were more likely to want a baby (70% vs 54%) and intend to have a baby (27% vs 12%) than same-age women in the general population.



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Blood transfusions during heart surgery increase risk of pneumonia

Patients who receive red blood cell transfusions during coronary artery bypass grafting (CABG) surgery are at an increased risk of developing pneumonia, researchers report. "Patients should receive red blood cell transfusions based on clinical need," an investigator noted. "Surgical teams may have opportunities to reduce the need for transfusions among patients, thereby reducing the risk of secondary complications."



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Novel simulation model improves training experience for cardiothoracic surgeons

A new surgical training model that simulates patient bleeding is providing cardiothoracic surgery residents with “real-life” experience without compromising patient safety, researchers report.



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Unique aortic aneurysm repair shows promise

A novel, minimally invasive approach appears safe for treating life-threatening aneurysms that occur in the deepest part of the aorta, making it easier for surgeons to repair the aorta without opening the chest and easier for patients to recover, experts report.



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SouthCoast Health receives national recognition as Patient-Centered Medical Home

SouthCoast Health, the Savannah-based medical organization formerly known as SouthCoast Medical Group, recently received national recognition as a Patient-Centered Medical Home (PCMH) by the National Committee for Quality Assurance.



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Even with copayments for nonurgent care, Medicaid patients still rely on ERs

To control costs and encourage Medicaid recipients to get primary care doctors, some states charge copayments to Medicaid patients who got nonurgent care in hospital emergency departments. A new study based on 2001-2010 data finds copayments did not affect the rate of Medicaid patients' emergency room visits or lead to more primary care doctor's office visits.



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Patients dismissing 'trivial' symptoms could delay cancer diagnosis

People who dismiss their symptoms as trivial or worry about wasting the doctor's time may decide against going to their GP with red-flag cancer warning symptoms, according to a study.



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Heart surgeons explore changing patterns in care of patients with aortic dissection

Cardiothoracic surgeons have long played a central role in caring for patients with aortic dissection, a life-threatening condition that in the past was treated only with open surgery or medicines. But according to a new study, thanks to new minimally invasive endovascular procedures, other specialists are becoming increasingly involved in the management of patients with aortic dissection.



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Take This Quick Quiz To See If You're Ready To Lose Belly Fat

You need to ask yourself a few questions to decide if you're ready to lose belly fat. If you answer yes to these questions, you really are ready and now you need to take action.



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More than half of ICU patients on ventilators have the ability to communicate

More than half of patients in intensive care units (ICU) using ventilators to help them breathe could benefit from assistive communication tools, a new study has concluded. "Our findings challenge the commonly held assumption of many clinicians and researchers that these patients are unable to communicate or participate in their care," said a co-author of the study.



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Care eliminates racial disparity in colon cancer survival rates, study finds

More equitable delivery of evidence-based care can close a persistent racial disparity in colon cancer survival rates in the United States. African-American patients have consistently had lower survival rates when compared with white patients, despite a nationwide decline in colon cancer deaths overall.



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Bpifrance awards TxCell EUR 1.7 million grant for clinical development of Ovasave

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, today announces the receipt of EUR 1.7 million from Bpifrance.



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Neuromod Devices, Irish Tinnitus Association announce launch of Tinnitus Awareness Week 2015

Saturday 31st of January sees the launch of Tinnitus Awareness Week. This year a public event will take place, hosted by The Neuromod Clinic in conjunction with the Irish Tinnitus Association. This free of charge event will take place at The Hermitage Medical Clinic, Lucan, Dublin at 10.30am on Saturday the 31st January.



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Tackling preventable blindness: a House of Commons reception review

“Macular degeneration is not life threatening, but it is life changing,” these were the words of Michael Valenzia, of the Macular Society at the recent House of Commons Reception held by AMD Alliance International.



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Genticel announces positive DSMB recommendation for ProCervix Phase 2 study in women with HPV

Genticel, a French biotechnology company and leading developer of therapeutic vaccines, announces today that the Data and Safety Monitoring Board, an independent committee of experts which monitors safety data every six months during the study, met as scheduled on January 22nd. It recommended the RHEIA-VAC study proceed without any modifications.



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Dexcom G4 PLATINUM Continuous Glucose Monitoring System with Share receives FDA approval

DexCom, Inc., a leader in continuous glucose monitoring (CGM) for patients with diabetes, announced today that it has received U.S. Food and Drug Administration approval for its Dexcom G4 PLATINUM Continuous Glucose Monitoring System with Share.



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What Is the Low Carbohydrate Diet?

One form of dieting that has been around for a long time is that related to the concept of massively reducing your carbohydrate intake. It is though, in some quarters, a highly controversial approach to losing weight.



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Factors That Increase the Risk of Varicose Veins

Essentially, this condition occurs when the veins have become enlarged and twisted just under the skin. There are actually a number of causes to varicose veins. Many of these conditions may be avoided while others are predetermined.



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7 Easy Makeup Tips for Beginners

Good makeup not only adds grace in your personality, it helps you look young. Being a beginner, you might feel that you cannot do the makeup like a professional. Do not worry. This article will present some of the best makeup tips for beginners. You will be able to wear makeup like a professional. The basic rules are the same. So, let's start.



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New study may lead to novel drug target for treating lung cancer

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer.



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Penn scientists explore potential therapeutic target for cerebral cavernous malformations

Tens of millions of people around the world have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations (CCMs). These abnormal growths can lead to seizures, strokes, hemorrhages, and other serious conditions, yet their precise molecular cause has never been determined.



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High cholesterol in mid-life can impact heart health later

Most young adults might assume they have years before needing to worry about their cholesterol.



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Mayo Clinic study compares new breast cancer risk prediction model with current model

A new breast cancer risk prediction model combining histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk than the current screening standard.



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CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Now researchers at Children's Hospital Los Angeles have designed and developed a new protein-based therapy they believe will prove highly effective against drug-resistant leukemia cells.



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Study shows differences in play behavior, brain activation patterns and stress levels in autistic children

Brain scans confirm significant differences in play behavior, brain activation patterns and stress levels in children with autism spectrum disorder (ASD) as compared with typically developing children.



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NovellusDx presents data from studies on Precision Cancer Analysis platform at PMWC 2015

NovellusDx, the leading Precision Cancer Analysis company delivering actionable intelligence about the mutational hierarchies that drive each patient’s cancer progression, announced today that the company will highlight data from studies on its Precision Cancer Analysis platform, at the Personalized Medicine World Conference 2015 in Silicon Valley.



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Study: Poor psychosocial work environment linked to cardiovascular problems

A psychosocially poor work environment means that employees experience highly demanding requirements but have little ability to control their work or not feel sufficiently appreciated for the contributions they make.



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Ethicon launches new ECHELON FLEX Powered Vascular Stapler for lung cancer treatment

Ethicon has developed a new powered vascular stapler designed to provide greater precision and stability than currently available staplers for critical vessel transections. The new ECHELON FLEX Powered Vascular Stapler has the narrowest anvil of any stapler on the market, an articulating shaft and advanced placement tip that may allow for better visibility, navigation and precise placement during thoracic and other procedures, including VATS lobectomy (Video-Assisted Thoracoscopic Surgery) for lung cancer.



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Deprived, ethnic minority areas in England worst affected by air pollution

A new study has found big differences in air pollution across communities in England, with deprived and ethnic minority areas the worst affected.



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Majority of Canada's homeless adults with mental illness show evidence of cognitive deficits

Nearly three-quarters of homeless adults with mental illness in Canada show evidence of cognitive deficits, such as difficulties with problem solving, learning and memory, new research has found.



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Pitt researchers receive NIH grant to improve health of sedentary, overweight people

University of Pittsburgh Graduate School of Public Health researchers are flipping conventional thought on its head regarding how to improve the health of sedentary people at risk for diabetes and heart disease in a new study designed to combat a condition popularly called "sitting disease."



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Increased levels of stress hormones in mother can affect foetal development

Increased levels of stress hormones can lead pregnant mice to overeat, but affect growth of the foetus and, potentially, the long term health of her offspring, according to a study published today.



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University of Colorado, Mile High Ophthalmics sign licensing agreement for new cataract surgery device

A new device designed to perform safer, more effective cataract surgery is going on the market following a licensing agreement between the University of Colorado and Mile High Ophthalmics LLC.



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Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers.



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Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Scientists at the University of Saskatchewan College of Medicine, Department of Physiology, Saskatoon, Canada, led by Dr. Joseph Fomusi Ndisang have determined that upregulating heme-oxygenase with hemin improves pericardial adipocyte morphology and function.



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Imperial College professor honored with Helmholtz International Fellow Award

The British cell biologist Professor Amanda Gay Fisher of Imperial College London has been honored with the Helmholtz International Fellow Award for her excellent research. Fisher is one of seven outstanding researchers from abroad who received the award, each of which is endowed with 20,000 euros. According to the Helmholtz Association, Germany's largest scientific organization, the award also includes an invitation to visit one or several Helmholtz research centers.



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Researchers find methods to manipulate natural proteins that self-assemble into amyloid fibrils

Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled plaques associated with Alzheimer's disease -- but similar proteins can also form very useful materials, such as spider silk, or biofilms around living cells.



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Study explores economic outcomes of hospital-based violence intervention

At more than 25 hospitals across the U.S., health care professionals have embraced a public health approach to their work--taking action to prevent violent injuries, not just treat them. In programs known as hospital-based violence intervention programs (HVIPs), teams of medical professionals, social workers and researchers step in at a critical moment in a patient's life--the period following a violent injury such as a gunshot or stab wound--with case management, counseling and other services that help these victims break free from the cycle of violence.



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Household rules, regular sleep-wake routines improve sleep in children

Children obtain better and more age-appropriate sleep in the presence of household rules and regular sleep-wake routines, according to sleep researchers.



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Morphine after tonsillectomy may be life threatening for children

Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.



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Progenitor cells responsible for generation and maintenance of Merkel cells

Researchers have identified a population of "progenitor" cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells. The study appears in The Journal of Cell Biology.



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Alcohol drinking pattern influences risk of cirrhosis

Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently.



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