Review explores cancer screening, prevention, and treatment in people with mental illness

A new report suggests that healthcare system and societal factors are just as critical as individual lifestyle factors in creating health disparities among people with metal illness.

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Computer model could hold key to personalized epilepsy treatment

A computer model that identifies the parts of a person's brain responsible for epileptic seizures could be used to design personalized surgical procedures, researchers say.

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T-DM1 improved overall survival for heavily pretreated patients with HER2-pos breast cancer

Among patients with HER2-positive, metastatic breast cancer that had progressed despite treatment with two or more forms of HER2-targeted therapy (trastuzumab [Herceptin] and lapatinib [Tykerb]), median overall survival was increased for those treated with trastuzumab emtansine (T-DM1 [Kadcyla]) compared with those who received treatment of physician's choice, according to results from the phase III TH3RESA clinical trial.

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Controversial prostate cancer screening can be improved by repeating abnormal tests

For more than 20 years, the prostate-specific antigen (PSA) test has been used to help screen for prostate cancer, but in recent years, some task forces have called for this blood test to be abandoned because it leads to many unnecessary biopsies. Now, a new study shows that simply repeating abnormal PSA tests dramatically reduces unnecessary biopsies.

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Breast-conserving therapy yielded better outcomes than mastectomy for early-stage patients

Among patients with early-stage breast cancer, those who received breast- conserving surgery plus radiation therapy had improved overall survival after 10 years compared with those who received mastectomy without radiation therapy, according to new data.

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Blood samples analysis finds ESR1 gene mutations prevalent, associated with worse overall survival

Among patients with estrogen receptor (ER)-positive, metastatic breast cancer, those who had a D538G and/or a Y537S mutation in the estrogen receptor 1 (ESR1) gene, as detected in cell-free DNA obtained from patient blood samples, had significantly worse median overall survival, according to new data.

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Potential of liquid biopsy for breast cancer patients

Information gleaned from a liquid biopsy may help predict how individual women with advanced breast cancer will respond to certain therapies as well as reveal genetic mutations that can impact prognosis, according to two new studies.

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