BRCA1/2 analysis: an interview with Jurgi Camblong, CEO of Sophia Genetics

BRCA1 and BRCA2 genes are two of the most well studied genes in the cancer field. They are tumor suppressors - mutations in these genes can lead to breast and/or ovarian cancer. Predispositions can be detected in women before they develop cancer.



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Hospitals helping violence victims could save millions

In the first systematic look at the economic outcomes of hospital-based violence intervention, researchers demonstrate that, in addition to transforming victims' lives, these programs may indeed save a significant amount of money compared to non-intervention, in various sectors including health care and criminal justice, up to about $4 million to serve 90 clients in a 5-year period.



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Beetroot juice improves exercise function of COPD patients, study shows

A study to investigate the effects of acute beetroot juice ingestion on the exercise capacity of COPD patients shows some promise, but a larger clinical trial is needed to verify results, scientists report.



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Should hospitals keep cardiac catheterization labs open on weekends?

Early intervention on weekdays and weekends in patients with Non-ST-Segment Elevation Acute Coronary Syndromes may be more cost-effective for both high-risk and low-risk cases, experts report.



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NMR in cancer research: an interview with Andy Byrd

My research these days is generally classified as structural biology, although as I trained in chemistry. I specialize in nuclear magnetic resonance (NMR) applied to biological problems. Our lab is very interested in studying mammalian proteins, particularly systems involved in cancer, in order to try to understand mechanisms to provide that information for our collaborators, and for the general knowledge of the community as well.



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Phase 1 clinical trial of CUDC-101 'throws kitchen sink' at head and neck cancer

At 18 months median follow up of a phase 1 clinical trial, one patient's cancer had worsened, two had died, and nine remained free of disease. Testing of blood and tumor samples showed that CUDC-101 had indeed inhibited the action of EGFR, HDAC and Her2.



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Higher dementia risk linked to more use of common drugs

A large study links a significantly increased risk for developing dementia, including Alzheimer's disease, to taking commonly used medications with anticholinergic effects at higher doses or for a longer time. Many older people take these medications, which include nonprescription diphenhydramine (Benadryl).



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